Potential value of guard-wire technology in the interventional treatment for ostial coronary lesions

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RESEARCH ARTICLE

Open Access

Potential value of guard‑wire technology in the interventional treatment for ostial coronary lesions Xiaoqiong Wang1, Xuemei Zong2, Bingqiang Li1, Zhanying Han3, Xinjie Duan1, Ying Li1, Jing Zhang1, Yaohui Wang1*  and Yaoli Wang4

Abstract  Background:  To explore potential value of guard-wire technology during percutaneous coronary intervention (PCI) in patients with ostial coronary lesions. Methods:  Patients, who underwent PCI, were collected between October 2011 and March 2017. Of the 141 patients, 63 (44.7%) have ostial lesions, and 78 (55.3%) have distal bifurcation sites. They were divided into group A (n = 71) and group B (n = 70). Group A received PCI after guard-wire technology. Group B were given balloon dilation and stent after placing guide wire through target lesion vessel. X-ray exposure time, contrast agent dosage, total PCI duration, pressure incarceration times, cases of malignant arrhythmia and cases of failed PCI of all patients were analyzed, respectively. Results:  The general clinical characteristics includes patients age, sex ratio, the proportion of complications, smoking ratio and left ventricular ejection fraction of both groups was not significantly different. X-ray exposure time, contrast agent dosage, PCI total time, stent positioning time, pressure infestation frequency, arrhythmia frequency and complication number of group B were higher than those of group A. There is no case of malignant arrhythmia and case of failed PCI in group A, while there were five malignant arrhythmia and four failed PCI in group B. Contrast agent dosage and cases of failed PCI increased in group B compared with group A. Conclusion:  The guard wire technology is safer and more feasible to patients with ostial coronary lesions who underwent PCI. Keywords:  Ostial lesions, Guard-wire technology, Aortasinus-in guard-wire technology, Branch guard-wire technology Background Ostial coronary lesions (AOL) are defined as a stenosis > 50% within 3 mm of the orifice in right coronary artery (RCA) or left main coronary artery (LMCA). The majority of ostial coronary lesions are due to atherosclerotic *Correspondence: [email protected] 1 Department of Cardiology, The First People’s Hospital of Pingdingshan City (The First Affiliated Hospital of Pingdingshan University), 117 Youyue Road, Weidong District, Pingdingshan 467000, Henan Province, China Full list of author information is available at the end of the article

coronary artery disease. Fibrocellular and sclerotic fragments were the major tissue components in coronary lesions. An ostial lesion is characterized by a rigid fibrotic texture with pronounced sclerosis associated with a very high tendency to recoil, and this may lead to a higher complication rate and a higher rate of restenosis in primary interventional result. Despite the introduction of various new technologies, vascular lumen of the right coronary artery are more challenging for percutaneous interventional treatment with a higher restenosis rate [1].

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