Safety and effectiveness of coronary intravascular lithotripsy in eccentric calcified coronary lesions: a patient-level
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ORIGINAL PAPER
Safety and effectiveness of coronary intravascular lithotripsy in eccentric calcified coronary lesions: a patient‑level pooled analysis from the Disrupt CAD I and CAD II Studies Florian Blachutzik1 · Benjamin Honton2 · Javier Escaned3 · Jonathan M. Hill4 · Nikos Werner5 · Adrian P. Banning6 · Alexandra J. Lansky7 · Sophia Schlattner1 · Bernard De Bruyne8 · Carlo Di Mario9 · Oliver Dörr1 · Christian Hamm1 · Holger M. Nef1 Received: 2 July 2020 / Accepted: 21 August 2020 © The Author(s) 2020
Abstract Background The aim of this study was to assess the safety and effectiveness of intravascular lithotripsy (IVL) in treating eccentric calcified coronary lesions. Methods Between December 2015 and March 2019, 180 patients were enrolled in the Disrupt CAD I and CAD II studies across 19 sites in 10 countries. Patient-level data were pooled from these two studies (n = 180), within which 47 eccentric lesions (26%) and 133 concentric lesions were identified. Results Clinical success, defined as residual stenosis
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