Presence of dynapenia and association with anthropometric variables in cancer patients
- PDF / 558,230 Bytes
- 9 Pages / 595.276 x 790.866 pts Page_size
- 100 Downloads / 154 Views
RESEARCH ARTICLE
Open Access
Presence of dynapenia and association with anthropometric variables in cancer patients Ana Beatriz Rechinelli1, Isabele Lessa Marques1, Eduarda Cristina Rodrigues de Morais Viana1, Isadora da Silva Oliveira1, Vanusa Felício de Souza1, Glenda Blaser Petarli2, Jose Luiz Marques Rocha1,3 and Valdete Regina Guandalini1,3*
Abstract Background: Dynapenia is defined as an age-related loss of muscle strength. There is little information on dynapenia in cancer patients and on how it relates to anthropometric variables. The aim of this study was to analyze the presence of dynapenia and its association with anthropometric variables in hospitalized cancer patients. Methods: Participants comprised adult and elderly cancer patients evaluated within the first 48 h of hospital admission to a tertiary public hospital, a referral center for gastrointestinal tract surgery. Anthropometric variables were measured according to standardized protocols. Dynapenia was identified based on handgrip strength (HGS), according to the cutoff points defined by the European Working Group on Sarcopenia in Older People (EWGSOP2), with values for women < 16 kg and for men < 27 kg. Statistical analysis was performed using SPSS software, version 22.0, with a significance level of 5%. Results: This study included 158 patients aged in average 59.5 ± 14.0 years; of these, 53.6% were elderly, 58.9% nonwhite and 59.5% had some degree of malnutrition. The most prevalent type of cancer was that of the lower gastrointestinal tract (33.5%). The presence of dynapenia was observed in 23.4% of the patients and cachexia in 36.1%. There was an association between dynapenia with age (p < 0.001), life stage (p = 0.002) and race/color (p = 0.027), and also with body mass index (BMI) (p = 0.001) and adductor pollicis muscle thickness (APMT) of both hands (p < 0.05). After logistic regression analysis, adjusted for the sociodemographic variables, the APMT of the dominant hand and the low weight determined by body mass index remained associated with the occurrence of dynapenia (p < 0.05). (Continued on next page)
* Correspondence: [email protected] 1 Nutrition Course. Department of Integrated Health Education, Federal University of Espirito Santo, Vitoria, Espırito Santo, Brazil. Marechal Campos avenue, 1468 – Maruípe, Vitória, Espírito Santo CEP: 29040-090, Brazil 3 Postgraduate Program in Nutrition and Health, Federal University of Espirito Santo, Vitoria, Espırito Santo, Brazil. Avenida Marechal Campos avenue, 1468 – Maruípe, Vitória, Espírito Santo CEP: 29040-090, Brazil Full list of author information is available at the end of the article © The Author(s). 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images o
Data Loading...
