Pretreatment central quality control for craniospinal irradiation in non-metastatic medulloblastoma
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ORIGINAL ARTICLE
Pretreatment central quality control for craniospinal irradiation in non-metastatic medulloblastoma First experiences of the German radiotherapy quality control panel in the SIOP PNET5 MB trial Stefan Dietzsch1 · Annett Braesigk1 · Clemens Seidel1 · Julia Remmele1 · Ralf Kitzing1 · Tina Schlender1 · Martin Mynarek2 · Dirk Geismar3 · Karolina Jablonska4 · Rudolf Schwarz5 · Montserrat Pazos6 · Marc Walser7 · Silke Frick8 · Kristin Gurtner9 · Christiane Matuschek10 · Semi Ben Harrabi11 · Albrecht Glück12 · Victor Lewitzki13 · Karin Dieckmann14 · Martin Benesch15 · Nicolas U. Gerber16 · Stefan Rutkowski2 · Beate Timmermann3 · Rolf-Dieter Kortmann1 Received: 24 June 2020 / Accepted: 23 October 2020 © The Author(s) 2020
Abstract Purpose Several studies have demonstrated the negative impact of radiotherapy protocol deviations on tumor control in medulloblastoma. In the SIOP PNET5 MB trial, a pretreatment radiotherapy quality control (RT-QC) program was introduced. A first analysis for patients enrolled in Germany, Switzerland and Austria with focus on types of deviations in the initial plan proposals and review criteria for modern radiation technologies was performed.
Beate Timmermann and Rolf-Dieter Kortmann share last authorship. Data sharing statement Research data are stored in an institutional repository and will be shared upon request to the corresponding author.
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Center for Protontherapy, Paul Scherrer Institute, Villigen, Switzerland
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Department of Radiotherapy and Radiation Oncology, Hospital Bremen Mitte, Bremen, Germany
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Department of Radiotherapy and Radiation Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technical University Dresden, Dresden, Germany
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Department for Radiation Oncology, University of Leipzig Medical Center, Stephanstr. 9a, 04103 Leipzig, Germany
Department of Radiation Oncology, Medical Faculty Heinrich Heine University Duesseldorf, Duesseldorf, Germany
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Departement of Pediatric Hematology and Oncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany
Department of Radiation Oncology and Radiotherapy, Heidelberg University Hospital, Heidelberg, Germany
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Radiation Oncology, Munich-Schwabing Municipal Hospital, Munich, Germany
Electronic supplementary material The online version of this article (https://doi.org/10.1007/s00066-020-01707-8) contains supplementary material, which is available to authorized users. Dr. med. Stefan Dietzsch, MD
[email protected] 1
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Clinic for Particle Therapy, West German Proton Therapy Centre, University of Essen, Essen, Germany
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Department of Radiotherapy, University of Wuerzburg, Wuerzburg, Germany
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Faculty of Medicine, Department of Radiation Oncology, University of Cologne, Cologne, Germany
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Department of Radiotherapy, Medical University of Vienna, Vienna, Austria
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Department of Radiation Oncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany
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Department of Radiotherapy and Radiation Oncology, Ludwig Maximilian Un
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