Profile of Dr. Xiaojiang Hao

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https://doi.org/10.1007/s11427-020-1812-6

•PROFILE•

Profile of Dr. Xiaojiang Hao Dr. Xiaojiang Hao graduated from the Department of Chemistry, Guizhou University in 1976, and obtained his Master’s degree of Science from Kunming Institute of Botany (KIB), Chinese Academy of Sciences (CAS) in 1985 and Ph.D. degree in Pharmacy from the Institute for Chemical Research, Kyoto University in 1990. In 1991, he returned to KIB, CAS as an associate professor, and served as Chair of the Department of Phytochemistry. In 1994, he was promoted to a full professor at the current institute. He served as the Deputy Director of KIB and Director of Open Laboratory of Phytochemistry from 1995 to 1997, and Director of KIB from 1997 to 2005. He was awarded Outstanding Young Talent from the National Natural Science Foundation of China in 1995, the First Prize for Natural Sciences in Yunnan Province for three times (2003, 2009, and 2013), and the Science and Technology Innovation Award of the Ho Leung Ho Lee Foundation in 2017. In 2019, he was elected as Member of the Chinese Academy of Sciences. Dr. Hao is currently a professor of the State Key Laboratory of Phyotchiemstry and Plant Resources in West China, KIB, CAS. His research interest is in the area of plant resources, phytochiemstry, and chemical biology of plant natural products.

Identification of novel phytochemical structures from diverse plants in Southwest China China is rich in plant resources. In particular, Yunnan province is known as the “Kingdom of Plants” and the “Treasure of Drugs”. For more than 40 years, Dr. Hao has focused on the field of Natural Product Sciences of Plants, and has dedicated his life to medicinal plant chemistry and natural product research in Southwest China. Since 1991, the Hao’s team has studied the chemical components of more than 200 species of plants and identified more than 6,000 chemical constituents including 1,500 new structures and 102 new scaffolds (Cai et al., 2012; Cao et al., 2014; Di et al., 2007;

Fan et al., 2015; Fang et al., 2008; Fang et al., 2015; Gao et al., 2007; Huang et al., 2013; Li et al., 2007a; Lv et al., 2016; Tan et al., 2010; Tian et al., 2016; Wang et al., 2007; Zhang et al., 2009a; Zhang et al., 2009b; Zhao et al., 2013). Hao’s laboratory has become one of the most important discoverers of new Daphniphyllum alkaloids (Di et al., 2007; Li et al., 2007a; Wang et al., 2014; Xu et al., 2011; Zhang et al., 2009a; Zhang et al., 2009b). “The research on novel structure alkaloids of Daphniphyllum” won the First Class Award of Natural Science of Yunnan Province in 2009. These results were actually inspired by the hypothesis about the biosynthetic pathway of Daphniphyllum alkaloids that the “premature” involvement of amines in the formation of molecular skeletons leads to structural diversity of the Daphniphyllum alkaloids in the plants of the genus Daphniphyllum. That the structural diversity of plant natural products can be derived from the diversity of biosynthetic pathways is also mirrored by other new natural products