Prognosis of Neurological Diseases
This book offers clear, detailed guidance on all aspects of prognostic evaluation in patients who have been diagnosed with a neurological illness or have been involved in an accident with neurological consequences. It covers the full range of disorders of
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Prognosis of Neurological Diseases
Angelo Sghirlanzoni • Giuseppe Lauria Luisa Chiapparini Editors
Prognosis of Neurological Diseases
Editors Angelo Sghirlanzoni Fondazione “Giancarlo Quarta” Milan Italy
Luisa Chiapparini Istituto Neurologico C. Besta Milan Italy
Giuseppe Lauria Istituto Neurologico C. Besta Milan Italy
Under the auspices of
ISBN 978-88-470-5754-8 ISBN 978-88-470-5755-5 DOI 10.1007/978-88-470-5755-5
(eBook)
Library of Congress Control Number: 2015954242 Springer Milano Heidelberg New York Dordrecht London © Springer-Verlag Italia 2015 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. Printed on acid-free paper Springer-Verlag Italia Srl. is part of Springer Science+Business Media (www.springer.com)
Foreword
Clinical neurology has dramatically changed in the last years, mainly because of developments in new diagnostic tools and innovative disease-modifying therapies. Recently improved imaging and biomolecular techniques allow for more accurate diagnosis of many neurological disorders and, in some cases, for early and/or preclinical diagnosis, based on biomarkers, even before clinical manifestations. Moreover, new therapies are available for selected neurological disorders and have changed the natural history of these diseases. Based on these premises, the prognosis of most neurological disorders has changed in recent years, with wide implications for patients, their families and for the disease burden. Most textbooks of clinical neurology do not adequately focus on this aspect, although in everyday clinical practice, and especially when neurologists speak with patients and their relatives, they must repeatedly address questions regarding prognosis. Indeed, the outcome of a disease is the clinical question with the highest priority for both clinicians and patients. Prognosis of Neurological Diseases is based on a completely new perspective and aims to fill this gap in neurological literature. It covers the full range of disorders of the centr
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