Programmed Cell Death in Cancer Progression and Therapy
Programmed cell death (PCD) plays pivotal roles in tumor progression, cancer therapeutics and resistance of tumor cells to therapy. With the discovery of key mechanisms that are involved in mediating PCD and in promoting resistance to therapy, design of t
- PDF / 2,978,054 Bytes
- 362 Pages / 439.37 x 666.142 pts Page_size
- 88 Downloads / 217 Views
ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY Editorial Board: NATHAN BACK, State University of New York at Buffalo IRUN R. COHEN, The Weizmann Institute of Science ABEL LAJTHA, N.S. Kline Institute for Psychiatric Research JOHN D. LAMBRIS, University of Pennsylvania RODOLFO PAOLETTI, University of Milan
Recent Volumes in this Series Volume 607 EUKARYOTIC MEMBRANES AND CYTOSKELETON: ORIGINS AND EVOLUTION Edited by Gáspár Jékely Volumes 608 BREAST CANCER CHEMOSENSITIVITY Edited by Dihua Yu and Mien-Chie Hung Volume 609 HOT TOPICS IN INFECTION AND IMMUNITY IN CHILDREN VI Edited by Adam Finn and Andrew J. Pollard Volume 610 TARGET THERAPIES IN CANCER Edited by Francesco Colotta and Alberto Mantovani Volume 611 PETIDES FOR YOUTH Edited by Susan Del Valle, Emanuel Escher, and William D. Lubell Volume 612 RELAXIN AND RELATED PETIDES Edited by Alexander I. Agoulnik Volume 613 RECENT ADVANCES INTO RETINAL DEGENERATION Edited by Joe G. Hollyfield, Matthew M. LaVail, and Robert E. Anderson Volume 614 OXYGEN TRANSPORT TO TISSUE XXIX Edited by Kyung A. Kang Volume 615 PROGRAMMED CELL DEATH IN CANCER PROGRESSION AND THERAPY Edited by Roya Khosravi-Far and Eileen White
A Continuation Order Plan is available for this series. A continuation order will bring delivery of each new volume immediately upon publication. Volumes are billed only upon actual shipment. For further information please contact the publisher.
Roya Khosravi-Far • Eileen White
Programmed Cell Death in Cancer Progression and Therapy
Roya Khosravi-Far Harvard Medical School Boston, MA USA
ISBN 978-1-4020-6553-8
Eileen White Rutgers University Piscataway, NJ USA
e-ISBN 978-1-4020-6554-5
Library of Congress Control Number: 2007937291 © 2008 Springer Science + Business Media B.V. No part of this work may be reproduced, stored in a retrieval system, or transmitted in any form or by any means, electronic, mechanical, photocopying, microfilming, recording or otherwise, without written permission from the Publisher, with the exception of any material supplied specifically for the purpose of being entered and executed on a computer system, for exclusive use by the purchaser of the work. Printed on acid-free paper. 9 8 7 6 5 4 3 2 1 springer.com
Dedication
We dedicate this book to three deserving groups. First, our families for their support and encouragement, Simin, Ghasem, Reza and Ali Khosravi-Far, and Greg, Jason and Melissa Diamond. Second, to our students, fellows and assistants, who with their hard work pave the road to discovery. Last but not least, to anyone who has been touched by cancer, as they are our motivation for this work and for our research.
Contents
Foreword. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
ix
Contributors . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
xi
Chapter 1
Cell Death: History and Future . . . . . . . . . . . . . . . . . . . . . . . . Zahra Zakeri and Richard A. Lockshin
1
Chapter 2
Caspase Mec
Data Loading...
