Prominent coagulation disorder is closely related to inflammatory response and could be as a prognostic indicator for IC
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Prominent coagulation disorder is closely related to inflammatory response and could be as a prognostic indicator for ICU patients with COVID‑19 Yang Liu1 · Weibo Gao2 · Wei Guo3 · Yang Guo3 · Maojing Shi2 · Guiying Dong3 · Qinggang Ge4 · Jihong Zhu2 · Jin Lu1
© The Author(s) 2020
Abstract The new outbreak of Coronavirus Disease 2019 (COVID-19) has emerged as a serious global public health concern. A more in-depth study of blood coagulation abnormality is needed. We retrospectively analyzed 147 consecutive patients with COVID-19 who were admitted to three ICUs in Wuhan from February 9th, 2020 to March 20th, 2020. The baseline coagulation and other characteristics were studied. Our results showed that the prolonged PT, FDP, DD were positively correlated with the levels of neutrophils, ferritin, LDH, total bilirubin, multi-inflammation cytokines, and negatively correlated with the lymphocytes level (p
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