Prospective spine at risk program for prevalence of intracanal spine lesions in pediatric hereditary multiple osteochond
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Prospective spine at risk program for prevalence of intracanal spine lesions in pediatric hereditary multiple osteochondromas Catphuong L. Vu1 · Antionnette W. Lindberg1,2 · Viviana Bompadre2 · Klane K. White1,2 · Jennifer M. Bauer1,2 Received: 10 December 2019 / Accepted: 20 April 2020 © Scoliosis Research Society 2020
Abstract Study design Retrospective cohort study Objectives To determine prevalence of hereditary multiple osteochondromas (HMO) and utility of MRI surveillance in a prospective Spine at Risk (SAR) program. Summary of background data Unidentified intraspinal exostoses in HMO can lead to neurologic injury in children during sedated procedures but no MRI guidelines exist. We sought to determine the prevalence and age of intraspinal exostoses from MRIs, and indications for MRI surveillance. Methods Retrospective review was performed of pediatric HMO patients who underwent total spine MRIs at a single institution after a prospective SAR program was instituted. Charts were reviewed for MRI indication and findings, symptoms, surgery, and location of other exostoses. Fisher’s exact test was used to compare categorical variables and T test to compare continuous variables. Predictive value of pelvic/rib exostoses was calculated for intraspinal lesions. Results Forty-three patients with HMO underwent total spine MRIs with average age of 11.5 years. Fifteen (35%) patients had exostoses on vertebral column, eight (19%) had intra-canal spinal exostoses. Higher prevalence of spine lesions occurred in symptomatic patients than asymptomatic (any spinal lesion: 73% prevalence in symptomatic vs 22% in asymptomatic, p
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