Proteomic Methods in Neuropsychiatric Research
Due to continuous technical developments and new insights into the high complexity of neurological diseases, there is an increasing need for the application of proteomic technologies which can yield potential biomarker readouts for improved clinical manag
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Paul C. Guest Editor
Proteomic Methods in Neuropsychiatric Research
Advances in Experimental Medicine and Biology Proteomics, Metabolomics, Interactomics and Systems Biology
Series editor Daniel Martins-de-Souza University of Campinas (UNICAMP) Institute of Biology Laboratory of Neuroproteomics Campinas, Brazil
This series of volumes focuses on concepts, techniques and recent advances in the field of proteomics, interactomics, metabolomics and systems biology. Recent advances in various ‘omics’ technologies enable quantitative monitoring of myriad various biological molecules in a high-throughput manner, and allow determination of their variation between different biological states on a genomic scale. Now that the sequencing of various genomes, from prokaryotes to humans, has provided the list and linear sequence of proteins and RNA that build living organisms, defining the complete set of interactions that sustain life constitutes one of the key challenges of the postgenomic era. This series is intended to cover experimental approaches for defining protein-protein, protein-RNA, protein-DNA and protein-lipid interactions; as well as theoretical approaches dealing with data analysis, integration and modeling and ethical issues. More information about this series at http://www.springer.com/series/15040
Paul C. Guest Editor
Proteomic Methods in Neuropsychiatric Research
Editor Paul C. Guest Department of Biochemistry and Tissue Biology University of Campinas (UNICAMP) Campinas Brazil
ISSN 0065-2598 ISSN 2214-8019 (electronic) Advances in Experimental Medicine and Biology ISBN 978-3-319-52478-8 ISBN 978-3-319-52479-5 (eBook) DOI 10.1007/978-3-319-52479-5 Library of Congress Control Number: 2017935365 © Springer International Publishing AG 2017 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. Printed on acid-free paper This Springer imprint is pub
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