Psychometric evaluation of a Canadian version of the Seattle Angina Questionnaire (SAQ-CAN)
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RESEARCH
Psychometric evaluation of a Canadian version of the Seattle Angina Questionnaire (SAQ‑CAN) Oluwaseyi A. Lawal1 , Oluwagbohunmi Awosoga2, Maria J. Santana1, Matthew T. James1, Danielle A. Southern1, Stephen B. Wilton3, Michelle M. Graham4, Merrill Knudtson3, Mingshan Lu5, Hude Quan1, William A. Ghali1, Colleen M. Norris6 and Tolulope Sajobi1*for the APPROACH Investigators
Abstract Background: The Seattle Angina Questionnaire (SAQ) is a widely-used patient-reported outcomes measure in patients with heart disease. This study assesses the validity and reliability of the SAQ in a Canadian cohort of individuals with stable angina. Methods and results: Data are from the Alberta Provincial Project for Outcome Assessment in Coronary Heart Disease (APPROACH) registry, a population-based registry of patients who received cardiac catheterization in Alberta, Canada. The cohort consists of 4052 patients undergoing cardiac catheterization for stable angina and completed the SAQ within 2 weeks. Exploratory factor analysis and confirmatory factor analysis (CFA) were used to assess the factorial structure of the SAQ. Internal and test–retest reliabilities of a new measure (i.e., SAQ-CAN) was measured using Cronbach α and intraclass correlation coefficient, respectively. CFA model fit was assessed using the root mean square error of approximation (RMSEA) and comparative fit index (CFI). Construct validity of the SAQ-CAN was assessed in relation to Hospital Anxiety and Depression Scales (HADS), Euro Quality of life 5 dimension (EQ5D), and original SAQ. Of the 4052 patients included in this analysis, 3281 (80.97%) were younger than 75 years old, while 3239 (79.94%) were male. Both exploratory and confirmatory factor analyses revealed a four-factorial structure consisting of 16 items that provided a better fit to the data (RMSEA = 0.049 [90% CI = (0.047, 0.052)]; CFI = 0.975). The 16-item SAQ demonstrated good to excellent internal reliability (Cronbach’s α range from 0.77 to 0.90), moderate to strong correlation with the Original SAQ and EQ5D but negligible correlations with HADS. Conclusion: The SAQ-CAN has acceptable psychometric properties that are comparable to the original SAQ. We recommend its use for assessing coronary health outcomes in Canadian patients with Coronary Artery Disease. Keywords: Seattle Angina Questionnaire, Psychometric properties, Heart disease, Canadian, Stable angina, Healthrelated quality of life
*Correspondence: [email protected] 1 Department of Community Health Sciences, University of Calgary, 3280 Hospital Drive NW, Calgary, AB, Canada Full list of author information is available at the end of the article
Introduction Heart disease, the second-leading cause of death in Canada, affects up to 8.5% [1] of adult Canadians and accounts for an annual estimated cost of $21.2 billion [2]. In addition to conferring increased risks of premature mortality and major non-fatal morbidity, chronic heart disease leads to significant ongoing symptoms and associated impairment in functiona
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