Psychometric testing of the Skull Base Inventory health-related quality of life questionnaire in a multi-institutional s
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Psychometric testing of the Skull Base Inventory health‑related quality of life questionnaire in a multi‑institutional study of patients undergoing open and endoscopic surgery David Forner1 · Katrina Hueniken1 · Tom Yoannidis1 · Ian Witterick1 · Eric Monteiro1 · Gelareh Zadeh2 · Patrick Gullane1 · Carl Snyderman3 · Eric Wang3 · Paul Gardner3 · Benita Valappil3 · Dan M. Fliss4 · Barak Ringel4 · Ziv Gil5 · Shorook Na’ara5 · Eng H. Ooi6 · David P. Goldstein1 · Nidal Muhanna4 · Fred Gentili2 · John R. de Almeida1,7 Accepted: 8 August 2020 © Springer Nature Switzerland AG 2020
Abstract Purpose The skull base inventory (SBI) was developed to better assess health-related quality of life (HR-QOL) in patients with anterior and central skull base neoplasms treated by endoscopic and open approaches. The primary objective of this study was to prospectively assess the psychometric properties of the SBI. Methods This study is part of a multi-center study of patients undergoing endoscopic and open procedures completed between 2012 and 2018. Participants were eligible if they were over 18 years of age; had benign or malignant anterior, antero-lateral, or central skull base tumors; and required either an open or endoscopic skull base surgical approach. In order to assess the psychometric properties of the SBI, patients completed the instrument at six time points (preoperative, 2 weeks, 3 months, 6 months, 12 months postoperative). Patients also completed the Anterior Skull Base (ASB) questionnaire and the Sinonasal Outcome Test (SNOT-22) to allow comparison to the SBI. Results One hundred and eighty-seven patients were included across five centers, with 121 having an endoscopic procedure. Internal consistency (Cronbach’s alpha = 0.95) and test–retest at 12 months and 12 months plus 2 weeks (intraclass correlation > 0.90) were excellent. Concurrent validity was demonstrated by very strong correlation between total SBI scores and ASB scores (r = 0.810 to 0.869, p
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