A preliminary implementation of an active intraocular prosthesis as a new image acquisition device for a cortical visual
- PDF / 3,610,580 Bytes
- 8 Pages / 595.276 x 790.866 pts Page_size
- 89 Downloads / 157 Views
ORIGINAL ARTICLE Others
A preliminary implementation of an active intraocular prosthesis as a new image acquisition device for a cortical visual prosthesis Shinyong Shim1,2 · Kangmoon Seo3 · Sung June Kim1,2,4 Received: 7 January 2020 / Accepted: 7 April 2020 © The Japanese Society for Artificial Organs 2020
Abstract An active intraocular prosthesis is herein proposed as a new image acquisition device for a cortical visual prosthesis. A conventional intraocular prosthesis is a passive device that helps blind patients underwent eye enucleation to maintain the shape of an eyeball. In contrast, an active intraocular prosthesis, which works as an implantable wireless camera, can capture real-time images and transmit them to a cortical visual prosthesis to restore partial vision of the patients. This active device has distinct advantages in that it can garner a variety of image information while focusing on objects in accordance with natural eye movements, compared with a glasses-mounted camera and implanted micro-photodiodes in typical artificial vision systems. Coated with an epoxy and sealed by an elastomer for biocompatibility as well as durability, the active intraocular prosthesis was fabricated in a spherical form miniaturized enough to be inserted into the eye. Its operation was evaluated by wireless image acquisition displaying a processed gray-scale image. Furthermore, signal-to-noise ratio measurements were conducted to find a reliable communication range of the fabricated prosthesis, while it was covered by an 8-mm-thick biological medium that mimicked in vivo environments. In conclusion, the feasibility of the active intraocular prosthesis to cooperate with a cortical visual prosthesis is discussed. Keywords Active intraocular prosthesis · Implantable wireless camera · Image acquisition approach · Artificial vision · Cortical visual prosthesis
Introduction
* Sung June Kim [email protected] Shinyong Shim [email protected] Kangmoon Seo [email protected] 1
Department of Electrical and Computer Engineering, College of Engineering, Seoul National University, Seoul 08826, South Korea
2
Inter‑university Semiconductor Research Center, College of Engineering, Seoul National University, Seoul 08826, South Korea
3
Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Seoul National University, Seoul 08826, South Korea
4
Institute on Aging, College of Medicine, Seoul National University, Seoul 08826, South Korea
Artificial vision, referred to as a visual prosthesis, is an implantable electronic device intended to restore the partial vision of blind patients by stimulating their retinal cells, optic nerve, or visual cortex. Many clinical trials have proven that the blind with artificial vision can normally perform several basic tasks, such as localizing light, discriminating patterns, and reading characters [1–3]. Especially retinal prostheses are already commercialized and recently treat retinal degenerative diseases worldwide [3–5]. Every artificial vision needs an image s
Data Loading...
