Aging of Organisms
Biological aging as the time-depending general decline of biological systems associated with a progressively increasing mortality risk is a general phenomenom of great significance. The underlying processes are very complex and depending on genetic and en
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BIOLOGY OF AGING AND ITS MODULATION VOLUME4
AGING OF ORGANISMS Edited by
HEINZ D. OSIEWACZ J W Goethe University
Frankfurt Germany
SPRINGER-SCIENCE+BUSINESS MEDIA, B.V.
Library of Congress Cataloging-in-Publication Data is available.
ISBN 978-90-481-6332-8
ISBN 978-94-017-0671-1 (eBook)
DOI 10.1007/978-94-017-0671-1
Printed on acid-free paper
All Rights Reserved
© 2003 Springer Science+Business Media Dordrecht Originally published by Kluwer Academic Publishers in 2003 Softcover reprint of the hardcover 1st edition 2003 No part of this publication may be reproduced or utilized in any form or by any means, electronic, mechanical, including photocopying, recording or by any information storage and retrieval system, without written permission from the copyright owner.
Contents
Editorial: About the series "Biology of aging and its modulation" S. Rattan
vn
Preface Heinz D. Osiewacz
IX
Chapter 1.
Yeast longevity and aging S. Michal Jazwinski
Chapter 2.
Aging and longevity in the filamentous fungus Podosporo anserina Heinz D. Osiewacz
31
Genetic, metabolic and environmental factors associated with aging in plants Karin Krupinska, Jon Falk and Klaus Humbeck
55
Aging in sponges Heinz C. Schroder, Matthias Wiens and Werner E. G. Muller
79
Aging and environmental conditions in insects Klaus-GUnter Collatz
99
Chapter 3.
Chapter 4. Chapter 5. Chapter 6. Chapter 7. Chapter 8. Chapter 9. Chapter 10.
Genetics of aging in Drosophila Linda Partridge and Scott D. Pletcher
125
Aging in C. elegans Anders Olsen, James N Sampayo and Gordon J. Lithgow
163
Aging in birds Donna J. Holmes
201
Exploring the mechanism of aging using rodent models Yuji !keno and Holly Van Remmen
221
Human aging and longevity: genetic aspects Holger Hoehn and Armin Renner
247
Index
271
About the series "Biology of aging and its modulation" During the last 40 years, the study of the biological basis of aging has progressed tremendously, and it has now become an independent and respectable field of study and research. Several universities, medical institutes and research centers throughout the world now offer full-fledged courses on biogerontology. The interest of students taking such courses, followed by undertaking research projects for MSc and PhD studies, has also increased significantly. Cosmetic, cosmeceutical and pharmaceutical industry's ever increasing interest in aging research and therapy is also obvious. Moreover, increased financial support by the national and international financial agencies to biogerontological research has given much impetus to its further development. This five-volume series titled "Biology of Aging and its Modulation" fulfills the demand for books on the biology of aging, which can provide critical and comprehensive overview of the wide range of topics, including the descriptive, conceptual and interventive aspects of biogerontology. The titles of the books in this series and the names of their respective editors are: 1. 2. 3. 4. 5.
Aging at the molecular level (Thomas von Zglinicki,
