Amobarbital Effects and Lateralized Brain Function The Wada Test
The intracarotid amobarbital (or Amytal) procedure is commonly referred to as the Wada test in tribute to Juhn Wada, the physician who devised the technique and performed the fIrst basic animal research and clinical studies with this method. Wada testing
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David W. Loring Kimford 1. Meador Gregory P. Lee Don W. King
Amobarbital Effects and Lateralized Brain Function The Wada Test
Springer-Verlag New York Berlin Heidelberg London Paris Tokyo Hong Kong Barcelona Budapest
David W. Loring Section of Behavioral Neurology Department of Neurology Medical College of Georgia Augusta, GA 30912-3275
Kimford J. Meador Section of Behavioral Neurology Department of Neurology Medical College of Georgia Augusta, GA 30912-3280
Gregory P. Lee Department of Psychiatry and Department of Surgery (Neurosurgery) Medical College of Georgia Augusta, GA 30912-4010
Don W. King Epilepsy Diagnostic and Treatment Unit Department of Neurology Medical College of Georgia Augusta, GA 30912-3200
With two figures. Library of Congress Cataloging-in-Publication Data Amobarbital effects and lateralized brain function: the Wada test I David W. Loring ... ret al.l. p. cm. Includes bibliographical references and index. ISBN-13: 978-1-4612-7704-0 e-ISBN-13: 978-1-4612-2874-5 DOl: 10.1007/978-1-4612-2874-5 I. Wada test.
2. Amobarbital- Diagnostic use.
I. Loring, David W. [DNLM: 1. Amobarbital-diagnostic use.
Tests. WL 103 A523l RC473.W34A48 1992 616.8'075 -dc20 DNLM/DLC for Library of Congress
3. Epilepsy.
2. Neuropsychological
91-5160
Printed on acid-free paper. © 1992 Springer-Verlag New York, Inc. Softcover reprint of the hardcover 1st edition 1992 All rights reserved. This work may not be translated or copied in whole or in part without the written permission of the publisher (Springer-Verlag New York, Inc., 175 Fifth Avenue, New York, NY 10010, USA), except for brief excerpts in connection with reviews or scholarly analysis. Use in connection with any form of information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed is forbidden. The use of general descriptive names, trade names, trademarks, etc., in this publication, even if the former are not especially identified, is not to be taken as a sign that such names, as understood by the Trade Marks and Merchandise Marks Act, may accordingly be used freely by anyone. Production managed by Hal Henglein; manufacturing supervised by Jacqui Ashri. Camera-ready copy prepared by the authors.
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Preface
The intracarotid amobarbital (or Amytal) procedure is commonly referred to as the Wada test in tribute to Juhn Wada, the physician who devised the technique and performed the fIrst basic animal research and clinical studies with this method. Wada testing has become an integral part of the preoperative evaluation for epilepsy surgery. Interestingly, however, Wada initially developed this method as a technique to assess language dominance in psychiatric patients in order that electroconvulsant therapy could be applied unilaterally to the non-dominant hemisphere. Epilepsy surgery has matured as a viable treatment for intractable seizures and is no longer confmed to a few major universities and medical ins
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