Analgesic and psychoactive medications and the risk of falls in relation to delirium in single-bed rooms compared to mul
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ORIGINAL ARTICLE
Analgesic and psychoactive medications and the risk of falls in relation to delirium in single‑bed rooms compared to multiple‑bed rooms in geriatric inpatients Sif Blandfort1 · Merete Gregersen1 · Kirsten Rahbek1 · Svend Juul2 · Else Marie Damsgaard1 Received: 24 May 2019 / Accepted: 21 August 2019 © Springer Nature Switzerland AG 2019
Abstract Background Previously, we demonstrated a substantial reduction of delirium incidence among geriatric patients after relocating from old hospital buildings with multiple-bed rooms to a new hospital with single-bed rooms. Aims To investigate whether (1) the reduced incidence of delirium in single-bed rooms was associated with a simultaneous change in medication use, (2) the relocation had affected the incidence of falls, (3) the use of analgesics and psychoactive medications was associated with the risk of delirium and falls. Methods We included 461 admissions to the old wards and 553 admissions to the new wards. Delirium was assessed by the Confusion Assessment Method. Data on drug use and falls during hospitalization were extracted from medical records. Results There was no difference in drug use between the wards. In the new wards, patients who had experienced delirium had a much higher risk of falls than patients without delirium, while in the old wards this contrast was small. The risk of delirium was increased among patients who received antipsychotic drugs and anti-dementia drugs, Patients who received these drugs had an insignificantly increased risk of falls. Conclusion Medication of analgesics and psychoactive drugs was similar in the old and new wards. In single-bed rooms, but not in multiple-bed rooms there was a much higher risk of falls among inpatients that developed delirium than among other patients. Patients who had used antipsychotics and anti-dementia drugs during hospitalization had increased risk of developing delirium and an insignificantly higher risk of falls. Keywords Geriatric · Hospital design · Single-bed room · Delirium · Falls · Analgesic · Psychoactive drug
Background Geriatric patients are characterized by multimorbidity, cognitive impairment, physical disability, malnutrition, falls, polypharmacy and iatrogenic complications, and dependence of personal assistance. All these characteristics increase the risk of delirium. Delirium is a common mental syndrome in hospitalized older patients with serious adverse implications and high health care costs [1]. During hospitalization, the risk of delirium varies from 11 to 42% in general medical * Sif Blandfort [email protected] 1
Department of Geriatrics, Aarhus University Hospital, Palle Juul‑Jensens Boulevard 99, 8200 Aarhus N, Denmark
Department of Public Health, Aarhus University, Bartholins Allé 2, 8000 Aarhus C, Denmark
2
inpatients, and for frail older inpatients prevalences up to 60% are described [1, 2]. In our geriatric department, the risk of delirium was reduced from 29% to 16% in connection with relocation from an old hospital with multi-bed rooms to a ne
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