Ankylosing spondylitis kyphosis surgical correction postoperative evaluation via SRS-22 domain investigation
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RESEARCH ARTICLE
Open Access
Ankylosing spondylitis kyphosis surgical correction postoperative evaluation via SRS-22 domain investigation Hao Zhang, XueSong Zhang*, Fanqi Hu, Wenhao Hu, Yao Wang and Yongyu Hao
Abstract Background: The SRS-22 is used to evaluate clinical outcomes in ankylosing spondylitis kyphosis patients. This study aimed to investigate the relationship between Scoliosis Research Society-22 (SRS-22) domains and satisfaction with management in patients who underwent surgical correction for ankylosing spondylitis kyphosis. The relationship between patient satisfaction and SRS-22 domain scores will feedback abundant information of therapeutic effect and significance for treatment guidance. Methods: In this work, 106 patients with ankylosing spondylitis kyphosis at a single institution, who underwent posterior spinal fusion of five levels or more to the sacrum, completed SRS-22 evaluation preoperatively and followed up for a minimum of 2-year postoperation. Wilcoxon tests were performed to compare preoperative with 2-year postoperative scores. Spearman correlations were investigated to evaluate associations between the 2-year treatment satisfaction and therapeutic effect in SRS-22 domain scores. Results: There were 12 females and 94 males with mean BMI of 16.4 kg/m2 and at the mean age of 46.3 years. All of the primary surgeries were treatments performed with mean follow-up of 26 months. A statistical improvement between paired pre- and 2-year postoperative SRS-22 domain scores and most radiographical parameters, commonly P ≤ 0.05, was designed and implemented. The majority of patients gave SRS-22 satisfaction score with 3. 0 or more (88.5%) or 4.0 or more (68.8%), which are consistent with the moderate ceiling effect. Spearman coefficient correlations between the SRS-22 domain scores and patient satisfaction were all statistically significant, and they were from low to strong: [Mental (0.30), Activity (0.71), Pain (0.25), and Appearance (0.40)]. Furthermore, correlations for all radiographical and operative parameters were from low to strong. Conclusion: SRS-22 Activity domain correlates strongest with patient satisfaction in ankylosing spondylitis kyphosis patients who have undergone surgical correction at 2-year follow-up. Keywords: Scoliosis Research Society-22 (SRS-22), Ankylosing spondylitis kyphosis, Pedicle subtraction osteotomy, Activity, Health-related quality of life (HRQOL)
Background Ankylosing spondylitis (AS) is a chronic inflammatory disease, primarily involving the sacroiliac joints and spinal column, in a caudal to cranial manner. Thoracolumbar kyphosis deformity leading to cosmetic and functional impairments with a decrease in the quality of life is common in late-stage patients, resulting in the inability to look ahead,
* Correspondence: [email protected] The Department of Orthopaedics, Chinese PLA General Hospital, Beijing, People’s Republic of China
lie flat, dyspnea, and dysphagia [1]. With the progresses of the surgical technic, such as multiple Smith-Petersen osteotomy
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