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Bleeding and heparin-induced thrombocytopenia : 3 case reports In a retrospective analysis of 43 patients conducted between May 2012 and 2018, three patients [ages and sexes not stated] were described, who developed bleeding or heparin-induced thrombocytopenia during treatment with heparin or argatroban for thromboprophylaxis [dosages, routes, duration of treatment to reactions onset and outcomes not stated]. Three patients, who were on ventricular assist device (VAD) support, started receiving treatment with heparin (2 patients) and argatroban (1 patient) as thromboprophylaxis. However, of the two patients who received heparin, one patient developed heparininduced thrombocytopenia and one patient developed heparin-related profuse bleeding; while the patient, who received argatroban developed bleeding. Consequently, the thromboprophylaxis therapy was changed to unspecified thrombin inhibitors [direct thrombin inhibitor] in the two patients who received heparin. Vanderpluym CJ, et al. Utilization and Outcomes of Children Treated with Direct Thrombin Inhibitors on Paracorporeal Ventricular Assist Device Support. ASAIO Journal 803517753 66: 939-945, No. 8, Aug 2020. Available from: URL: http://doi.org/10.1097/MAT.0000000000001093

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Reactions 28 Nov 2020 No. 1832