Biology of C Reactive Protein in Health and Disease

This book offers a comprehensive study of C-reactive protein (CRP) belonging to the pentraxin family, including a brief history of CRP, its structure, synthesis and evolution.  Focusing on the emerging role of CRP and its clinical application in the

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Biology of C Reactive Protein in Health and Disease

Biology of C Reactive Protein in Health and Disease

Waliza Ansar • Shyamasree Ghosh

Biology of C Reactive Protein in Health and Disease

Waliza Ansar Department of Zoology Behala College Kolkata, West Bengal, India

Shyamasree Ghosh National Institute of Science Education School of Biological Sciences Bhubaneswar, Odisha, India

ISBN 978-81-322-2678-9 ISBN 978-81-322-2680-2 DOI 10.1007/978-81-322-2680-2

(eBook)

Library of Congress Control Number: 2015960243 Springer New Delhi Heidelberg New York Dordrecht London © Springer India 2016 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. Printed on acid-free paper Springer (India) Pvt. Ltd. is part of Springer Science+Business Media (www.springer.com)

Dedicated to our family, PhD guide, and our adorable children

Preface

Good science always demands independent replication of new thoughts and experimental results and desertion of accepted or the so-called theories in light of more and more reliable evidence. Failure to comply with this trend leads to a tremendous damaging bad science, as with the falsely claimed association/relations between facts, observations, and results. The progress of good science also often requires providence, to make discoveries by accident and prudence of things not sought. Work on the pentraxin proteins, like C-reactive protein (CRP) since the 1970s, has benefited from abundant scientific serendipity, leading to modern-day routine clinical use of CRP measurements and the ongoing diverse research projects to explore the pathophysiological role of CRP in various diseases, be it cardiovascular disease, prominently different cancers, rheumatoid arthritis, infectious diseases, and many others. Some emerging progress has been evolving to extrapolate the role of CRP in new field of disease biology. Works are published regarding the role of CRP in mumps, testicular diseases, and different damaging conditions and some other works that need some promine