Cancer of Unknown Primary
This book presents an up-to-date and thorough overview of cancer of unknown primary, encompassing topics ranging from epidemiology, tumor biology, and prognostic factors through to the most recent diagnostic and therapeutic advances. All aspects of manage
- PDF / 5,177,870 Bytes
- 197 Pages / 439.43 x 683.15 pts Page_size
- 62 Downloads / 190 Views
123
Cancer of Unknown Primary
Alwin Krämer • Harald Löffler Editors
Cancer of Unknown Primary
Editors Alwin Krämer Clinical Cooperation Unit Molecular Hematology/Oncology German Cancer Research Center (DKFZ) and University of Heidelberg Heidelberg Germany
Harald Löffler Clinical Cooperation Unit Molecular Hematology/Oncology German Cancer Research Center (DKFZ) and University of Heidelberg Heidelberg Germany
ISBN 978-3-319-22580-7 ISBN 978-3-319-22581-4 DOI 10.1007/978-3-319-22581-4
(eBook)
Library of Congress Control Number: 2015952541 Springer Cham Heidelberg New York Dordrecht London © Springer International Publishing Switzerland 2016 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. Printed on acid-free paper Springer International Publishing AG Switzerland is part of Springer Science+Business Media (www. springer.com)
Contents
1
Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 Harald Löffler and Alwin Krämer
2
Epidemiology, Risk Factors, and Survival in CUP: Pointers to Disease Mechanisms . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5 Kari Hemminki
3
Biologic Features of CUP . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 27 Harald Löffler and Alwin Krämer
4
Prognostic Factors and Their Role in the Management of CUP . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 45 Harald Löffler and Alwin Krämer
5
Diagnostic Work-up of CUP: An Approach to Current Recommendations and Underlying Evidence . . . . . . . . . . . 67 Alwin Krämer and Harald Löffler
6
The Radiologist’s Approach to CUP . . . . . . . . . . . . . . . . . . . . . . . . . . . . 75 Philipp M. Kazmierczak, Axel Rominger, and Clemens C. Cyran
7
Cancer of Unknown Primary: The Pathologist’s Approach . . . . . . . . . 91 Albrecht Stenzinger and Wilko Weichert
8
Treatment of Disseminated CUP . . . . . . . . . . . . . . . . . . . . .
Data Loading...
