Capecitabine
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Capecitabine Hand-food syndrome in an elderly patient: case report A 65-year-old man developed hand-foot syndrome [erythrodysaesthesia] while receiving capecitabine for gastric cancer. The man started receiving capecitabine 1000 mg/m2 twice daily on days 1–14 of 21-day cycles. Ten days after the fourth cycle, he developed reddening, numbness and pain in his left palm and left sole. Physical examination revealed unilaterally erythematous skin scaling and changes on his left palm and sole. He was diagnosed with grade II hand-foot syndrome, and it was thought to be possibly related to capecitabine. Capecitabine was discontinued and the man received supportive treatment. One week later, the hand-foot syndrome disappeared. Disel U, et al. Unilateral hand-foot syndrome: An extraordinary side effect of capecitabine. Cutaneous and Ocular Toxicology 29: 140-142, No. 2, Jun 2010. Available from: URL: http://dx.doi.org/10.3109/15569521003699585 803023865 USA
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Reactions 10 Jul 2010 No. 1309
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