Cellulose technologies applied to biomedical purposes from the patentometric point of view
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ORIGINAL RESEARCH
Cellulose technologies applied to biomedical purposes from the patentometric point of view Marcelo Gomes Speziali
Received: 24 June 2020 / Accepted: 19 September 2020 Springer Nature B.V. 2020
Abstract This study focused on investigating the technological context of cellulose and its derivatives and their applications to the biomedical area. Therefore, patentometric analysis of patent documents was conducted. A scenario containing information related to the most prominent players in the biomedical area and the places with high relevance for biomedical cellulose technologies and its markets of interest was built. This study used several tools of patentometry to forecast when the use of commercial cellulose or cellulose derivatives might be replaced by the newly created ones. The analysis of technological maturity showed that, in a few years, the market will be saturated with biomedical products that use cellulose as one of its raw materials, and the known molecules
will be replaced by recently invented materials based on chemically modified cellulose. This study of patentometry related to technological specialization identified cellulose technologies applied to the treatment of eye or ocular diseases. The newest and most cited patents indicated the preference of companies to use commercial cellulose derivatives to formulate their biomedical products instead of creating new cellulose derivatives to be applied to their compositions. This methodology can help researchers and decision-makers choose the best way to undertake a project involving the technological applications of cellulose to medicine.
Electronic supplementary material The online version of this article (https://doi.org/10.1007/s10570-020-03477-z) contains supplementary material, which is available to authorized users. M. G. Speziali (&) Departamento de Quı´mica, Instituto de Cieˆncias Exatas e Biolo´gicas, Universidade Federal de Ouro Preto, Campus Morro do Cruzeiro s/n, Bauxita, Ouro Preˆto, MG 35400-000, Brazil e-mail: [email protected]
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Cellulose
Graphic abstract Patent big data analysis helping researches doing business using cellulose technologies
Keywords Patent landscape Patentometry Innovation Cellulose derivatives Industry
Introduction Cellulose is one of the most abundant and renewable biopolymers in nature. Moreover, cellulose is obtained and commercialized at a low cost. The usability of cellulose is well known and widely described in the literature. The molecular structure of cellulose consists of a polysaccharide with a linear chain of (b1 ? 4) linked to b-D-glucopyranose units. Each glucose unit possesses three hydroxyl groups, i.e., two secondary groups at positions C2 and C3 and one primary group at position C6. These hydroxyl groups can establish intramolecular and intermolecular hydrogen bonds, thereby forming crystalline structures. The differences between cellulose polymorphs are reflected in its intensive properties, and consequently, its techno
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