Characterization of women with gestational diabetes who failed to achieve glycemic control by lifestyle modifications
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MATERNAL-FETAL MEDICINE
Characterization of women with gestational diabetes who failed to achieve glycemic control by lifestyle modifications Eyal Krispin1,2 · Adi Ashkenazi Katz1,2 · Elyasaf Shmuel1,2 · Yoel Toledano1,2 · Eran Hadar1,2 Received: 25 July 2020 / Accepted: 28 August 2020 © Springer-Verlag GmbH Germany, part of Springer Nature 2020
Abstract Purpose To identify specific characteristics of women diagnosed with gestational diabetes who failed to achieve good glycemic control by lifestyle modifications only. Methods Retrospective analysis of women carrying a singleton pregnancy diagnosed with gestational diabetes. The cohort included 314 women who achieved good glycemic control by lifestyle modifications and 328 women who required antidiabetic medications. Lifestyle modifications included medical nutrition therapy and physical exercise recommendations. Anti-diabetic medications included either oral treatment with metformin or glyburide and\or insulin. Results Women in the lifestyle modifications group were younger (32.87 vs. 33.79 years, p = 0.012) and had lower prepregnancy body-mass-index (25.86 vs. 27.93 kg/m2, p
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