Continuous positive airway pressure in children with severe pneumonia: a meta-analysis

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LETTER TO EDITOR

Continuous positive airway pressure in children with severe pneumonia: a meta‑analysis Zhi‑Li Wang1 · Yu He1 · Zheng‑Xiu Luo1 Received: 14 April 2020 / Accepted: 22 April 2020 © Children’s Hospital, Zhejiang University School of Medicine 2020

Pneumonia is the leading cause of death among  children aged 1–59 months worldwide [1]. WHO recommends providing low flow oxygen by nasal cannula in pediatric patients with oxygen saturation  50% indicating significant heterogeneity [9]. To explore the potential causes of significant heterogeneity, we performed subgroup analyses for primary outcomes if data were sufficient. The factors including age, sample size, settings, and high-risk conditions were prespecified for subgroup analyses. Sensitivity analysis was conducted by removing crossover trails and those studies without the supervision of physicians respectively. P value