Dementia with Lewy Bodies Clinical and Biological Aspects
This book describes biological and clinical aspects of dementia with Lewy bodies (DLB), one of the most common types of progressive dementia, although in most cases the cause is unknown. The editor has made a major contribution to the understanding o
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Dementia with Lewy Bodies Clinical and Biological Aspects
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Dementia with Lewy Bodies
Kenji Kosaka Editor
Dementia with Lewy Bodies Clinical and Biological Aspects
Editor Kenji Kosaka Emeritus Professor Yokohama City University Yokohama, Japan
ISBN 978-4-431-55946-7 ISBN 978-4-431-55948-1 DOI 10.1007/978-4-431-55948-1
(eBook)
Library of Congress Control Number: 2016957400 © Springer Japan KK 2017 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. Printed on acid-free paper This Springer imprint is published by Springer Nature The registered company is Springer Japan KK The registered company address is: Chiyoda First Bldg. East, 3-8-1 Nishi-Kanda, Chiyoda-ku, Tokyo 101-0065, Japan
Preface
Dementia with Lewy bodies (DLB) is now well known to be the second most frequent dementia following Alzheimer disease (AD). Of all types of dementia, AD is known to account for about 50 %, DLB about 20 %, and vascular dementia (VD) about 15 %. Thus, AD, DLB, and VD are now considered to be the three major dementias. Although the first case of AD was reported by A. Alzheimer in 1906, the first case of DLB was reported by me and my colleagues in 1976. Following a series of our papers (1976–1990), the name “Dementia with Lewy bodies” was proposed in the first International Workshop on DLB, held in Newcastle upon Tyne, England, in 1995, with the results of the workshop reported in Neurology in 1996. The second workshop was held in Amsterdam in 1997, and the third was again held in Newcastle upon Tyne in 2003. The results of the third workshop were published in 2005, with the clinical diagnostic criteria then reported in Neurology. Those criteria have been used even up until the present. I organized the fourth International Workshop, held in Yokohama, Japan, in 2005. Since then, a fifth workshop has not been convened, for reasons not entirely clear to me; however, the International Conference on DLB was held in Washington, DC, in 2006. A similar international conference was held in
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