• PDF / 170,476 Bytes
• 1 Pages / 595.245 x 841.846 pts (A4) Page_size
• 49 Downloads / 191 Views

DOWNLOAD

REPORT

---

1

Dexmedetomidine/sufentanil Nausea: case report In a study, an adult patient [age and sex not stated] was described, who developed nausea following administration of dexmedetomidine and sufentanil as postoperative IV analgesia in thoracoscopic surgery. The patient was scheduled for video-assisted thoracoscopic surgery. Thirty minutes before entering the operating room, the patient received scopolamine. The patient received IV injection sufentanil 0.4 µg/kg along with propofol and cisatracurium besilate for induction of anaesthesia. Thereafter, anaesthesia was maintained with IV infusion of sufentanil 0.18–0.30 µg/(kg h) and propofol. Cisatracurium besilate was administered as needed during the surgery. Thirty minutes before the end of surgery, sufentanil was stopped and the patient was connected to the patient-controlled intravenous analgesia (PCIA) pump, which delivered sufentanil and dexmedetomidine. Drug formula of PCIA pump was as follows: sufentanil 2 µg/kg [0.032µg/(kg h)] plus dexmedetomidine 1.5 µg/kg [0.024 µg/(kg h)]. Dexmedetomidine was prepared in sodium chloride [saline solution]. Parameter settings of PCIA pump were as follows: continuous delivery at rate 4 mL/h, single delivery dose 2 mL/ round, delivery lock time 10 min and delivery limit 12 mL/h. Six hours after the surgery, the patient developed nausea. The patient was treated with palonosetron. Consequently, the patient’s nausea subsided. Author comment: Besides one patient who developed nausea, no other adverse reactions occurred. The use of 0.0400~0.0880 µg/(kg h) of [dexmedetomidine] combined with 0.032 µg/(kg h) of sufentanil in postoperative analgesia can safely and effectively control the postoperative pain of patients who received video-assisted thoracoscopic surgery. Tan X, et al. Dose-response Relationship of Dexmedetomidine Combined with Sufentail for Postoperative Intravenous Analgesia in Video-assisted Thoracoscopic Surgery. [Chinese]. Zhongguo Yi Xue Ke Xue Yuan Xue Bao 41: 373-378, No. 3, 30 Jun 2019. Available from: URL: https://www.ncbi.nlm.nih.gov/ 803432900 pubmed/31282332 [Chinese; summarised from a translation] - China

0114-9954/19/1778-0001/$14.95 Adis © 2019 Springer Nature Switzerland AG. All rights reserved

Reactions 9 Nov 2019 No. 1778