Diabetes mellitus increases mortality in acute pyelonephritis patients: a population study based on the National Health
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ORIGINAL PAPER
Diabetes mellitus increases mortality in acute pyelonephritis patients: a population study based on the National Health Insurance Claim Data of South Korea for 2010–2014 Bongyoung Kim1 · Rangmi Myung2 · Gheun‑Ho Kim1 · Myoung‑jae Lee2 · Jieun Kim1 · Hyunjoo Pai1 Received: 7 August 2019 / Accepted: 28 March 2020 © Springer-Verlag GmbH Germany, part of Springer Nature 2020
Abstract Objective Diabetes mellitus has been suspected to increase mortality in acute pyelonephritis (APN) patients and the goal of this study is to verify this suspicion with a large data set based on almost the entire population of South Korea. Methods A nationwide cohort study was conducted using a South Korean Health Insurance Review and Assessment Service claim database. We collected demographic and clinical information including comorbidities of patients with APN as the primary discharge diagnosis during 2010–2014. Then we compared the in-hospital mortality and recurrence of APN across the diabetes and non-diabetes groups. Results Among 845,656 APN patients, 12.4% had diabetes mellitus. The median age was 65 in the diabetes group, which was much higher than 47 in the non-diabetes group; the female proportion was 91–92% in both groups. The in-hospital mortality rate was higher in the diabetes group (2.6/1000 events in the diabetes group vs. 0.3/1000 in the non-diabetes group, P
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