Endoscopic Therapy for Barrett's Esophagus
Endoscopic Therapy is emerging as the preferred therapy for early neoplasia in Barrett's Esophagus. This volume provides the key decision making factors in determining endoscopic therapy for an individual patient. All current techniques and complications
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Richard E. Sampliner, MD
CLINICAL GASTROENTEROLOGY
Series Editor George Y. Wu University of Connecticut Health Center, Farmington, CT, USA
For further volumes: http://www.springer.com/series/7672
Endoscopic Therapy for Barrett’s Esophagus Edited by
RICHARD E. SAMPLINER, MD University of Arizona College of Medicine, USA
Editor Richard E. Sampliner College of Medicine University of Arizona P.O.Box 245028 Tucson AZ 85724-5028 AHSC 6406 USA [email protected] [email protected]
ISBN 978-1-60327-444-9 e-ISBN 978-1-60327-445-6 DOI 10.1007/978-1-60327-445-6 Springer Dordrecht Heidelberg London New York Library of Congress Control Number: 2009929319 C Humana Press, a part of Springer Science+Business Media, LLC 2009
All rights reserved. This work may not be translated or copied in whole or in part without the written permission of the publisher (Humana Press, c/o Springer Science+Business Media, LLC, 233 Spring Street, New York, NY 10013, USA), except for brief excerpts in connection with reviews or scholarly analysis. Use in connection with any form of information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed is forbidden. The use in this publication of trade names, trademarks, service marks, and similar terms, even if they are not identified as such, is not to be taken as an expression of opinion as to whether or not they are subject to proprietary rights. While the advice and information in this book are believed to be true and accurate at the date of going to press, neither the authors nor the editors nor the publisher can accept any legal responsibility for any errors or omissions that may be made. The publisher makes no warranty, express or implied, with respect to the material contained herein. Printed on acid-free paper Springer is part of Springer Science+Business Media (www.springer.com)
Preface Endoscopic therapy for Barrett’s esophagus (BE) has come of age. This is documented by the publication of a randomized controlled trial of one modality and an abstract of a randomized sham-controlled trial of another. The goal of this book is to highlight and detail the differing techniques of ablation for the elimination of neoplasia and intestinal metaplasia in BE. The authors are all experts in the utilization of endoscopic therapy for BE. The latest developments in technology and the most recent clinical data are reviewed. Additional chapters on endoscopic imaging modalities to detect dysplasia, decision making in the clinical arena, and cost-effectiveness of ablation round out this approach to the management of BE. High-grade dysplasia and early (intramucosal) adenocarcinoma should not lead to automatic esophagectomy in the current era. Familiarity with the availability of ablation techniques is essential for every clinician dealing with patients with Barrett’s esophagus. Richard E. Sampliner, MD
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Contents Preface . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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