Epidemiological analysis of 67 local COVID-19 clusters in Sichuan Province, China
- PDF / 1,736,536 Bytes
- 9 Pages / 595.276 x 790.866 pts Page_size
- 15 Downloads / 204 Views
RESEARCH ARTICLE
Open Access
Epidemiological analysis of 67 local COVID19 clusters in Sichuan Province, China Suling Mao1†, Ting Huang1†, Heng Yuan1, Min Li2, Xiaomei Huang3, Changxiao Yang1, Xingyu Zhou1, Xiuwei Cheng1, Qian Su1 and Xianping Wu1*
Abstract Background: This study was intended to investigate the epidemiological characteristics of COVID-19 clusters and the severity distribution of clinical symptoms of involved cases in Sichuan Province, so as to provide information support for the development and adjustment of strategies for the prevention and control of local clusters. Methods: The epidemiological characteristics of 67 local clusters of COVID-19 cases in Sichuan Province reported as of March 17, 2020 were described and analyzed. Information about all COVID-19 clusters and involved cases was acquired from the China Information System for Disease Control and Prevention and analyzed with the epidemiological investigation results taken into account. Results: The clusters were temporally and regionally concentrated. Clusters caused by imported cases from other provinces accounted for 73.13%; familial clusters accounted for 68.66%; the average attack rate was 8.54%, and the average secondary attack rate was 6.11%; the median incubation period was 8.5 d; a total of 28 cases met the criteria for incubation period determination, and in the 28 cases, the incubation period was > 14 d in 21.43% (6/28). a total of 226 confirmed cases were reported in the 67 clusters. Ten cases were exposed before the confirmed cases they contacted with developed clinical symptoms, and the possibility of exposure to other infection sources was ruled out; two clusters were caused by asymptomatic carriers; confirmed cases mainly presented with fever, respiratory and systemic symptoms; a gradual decline in the severity of clinical symptoms was noted with the increase of the case generation. Conclusions: Population movement and gathering restrictions and strict close contact management measures will significantly contribute to the identification and control of cases. Transmission during the incubation period and asymptomatic infections have been noted. Studies on the pathogenicity and transmissibility in these populations and on COVID-19 antibody levels and protective effects in healthy people and cases are required. Keywords: Cluster, COVID-19, Epidemiology
Background In later December 2019, a number of pneumonia cases of unknown etiology emerged in Wuhan, China. Around the Chinese New Year in 2020, the number of cases rose sharply, involving multiple provinces, municipalities and * Correspondence: [email protected] † Suling Mao and Ting Huang contributed equally to this work. 1 Sichuan Center for Disease Control and Prevention, No. 6 Zhongxue Road, Wuhou District, Chengdu 610,041, Sichuan, China Full list of author information is available at the end of the article
autonomous regions in China; at the same time, outbreaks were reported in many other countries including Japan, Korea, Italy and the United States. On March 11, 2020
Data Loading...
