Evaluation of pleural lesions after pleurodesis with OK-432 by fluorodeoxyglucose-positron emission tomography/CT

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Evaluation of pleural lesions after pleurodesis with OK‑432 by fluorodeoxyglucose‑positron emission tomography/CT Miki Nishimori1 · Rika Yoshimatsu1 · Hitomi Iwasa1 · Kana Miyatake1 · Noriko Nitta1 · Takashi Anayama2 · Takuji Yamagami1 Received: 8 May 2020 / Accepted: 26 July 2020 © The Japanese Society of Nuclear Medicine 2020

Abstract Objective  This study aimed to determine changes in FDG-PET/CT after pleurodesis with OK-432 and to investigate differences in the changes between non-malignant and malignant lesions. Methods  Study participants were 17 patients with a history of malignant chest disease who underwent FDG-PET/CT after pleurodesis using OK-432 and in whom pleural lesions were determined to be non-malignant (n = 8) or malignant (n = 9). FDG uptake (­ SUVmax) was counted on all pleural lesions. CT findings (CT attenuation, shape) of pleural lesions with increased FDG uptake were evaluated. Results  The number of patients with increased FDG uptake in the pleura differed significantly between the non-malignant group (3/8) and malignant group (9/9) (p