Evolutionary Bioinformatics

Now in its third edition and supplemented with more online material, this book aims to make the "new" information-based (rather than gene-based) bioinformatics intelligible both to the "bio" people and the "info" people. Books on bioinformatics have tradi

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Evolutionary Bioinformatics Third Edition

Evolutionary Bioinformatics

Donald R. Forsdyke

Evolutionary Bioinformatics Third Edition

Donald R. Forsdyke Department of Biomedical and Molecular Sciences Queen’s University Kingston, ON, Canada

ISBN 978-3-319-28753-9 ISBN 978-3-319-28755-3 DOI 10.1007/978-3-319-28755-3

(eBook)

Library of Congress Control Number: 2016931596 Springer Cham Heidelberg New York Dordrecht London © Springer International Publishing Switzerland 2006, 2011, 2016 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. Printed on acid-free paper Springer International Publishing AG Switzerland is part of Springer Science+Business Media (www.springer.com)

In memory of Erwin Chargaff whose studies of the base composition ‘accent’ of DNA underlie everything in this book, and of Susumo Ohno who first understood that DNA ‘speaks’ in palindromic verses; with many thanks to Vinay Prabhu whose neat little 1993 paper showed the way.

Erwin Chargaff (1905-2002)

Contents

Note on the Third Edition .............................................................................. xvii Note on the Second Edition ............................................................................ xix Abbreviations .................................................................................................. xxi Prologue: To Select is Not To Preserve .......................................................... xxiii Part I

Information and DNA

1

Memory: A Phenomenon of Arrangement ............................................ Priorities .................................................................................................... Textual and Hereditary Information.......................................................... Mental Information ................................................................................... Periodical Rhythms ................................................................................... Food ...............................................