Extramedullary plasmacytoma (EMP): Report of a case manifested as a mediastinal mass and multiple pulmonary nodules and
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BioMed Central
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Case report
Extramedullary plasmacytoma (EMP): Report of a case manifested as a mediastinal mass and multiple pulmonary nodules and review of literature Shi-Ping Luh*1, Yih-Shyong Lai2, Chung-Hong Tsai2 and Thomas ChangYao Tsao3 Address: 1Department of Surgery, Chung-Shan Medical University and Chia-Yi Christian Hospital, Taichung City, Taiwan, 2Pathology, Chung Shan Medical University and Hospital, Taichung City, Taiwan and 3Thoracic Medicine, Chung Shan Medical University and Hospital, Taichung City, Taiwan Email: Shi-Ping Luh* - [email protected]; Yih-Shyong Lai - [email protected]; Chung-Hong Tsai - [email protected]; Thomas Chang-Yao Tsao - [email protected] * Corresponding author
Published: 27 October 2007 World Journal of Surgical Oncology 2007, 5:123
doi:10.1186/1477-7819-5-123
Received: 29 July 2007 Accepted: 27 October 2007
This article is available from: http://www.wjso.com/content/5/1/123 © 2007 Luh et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract Background: Extramedullary plasmacytoma (EMP) is a rare plasma cell neoplasm of soft tissue without bone marrow involvement or other systemic characteristics of multiple myeloma Case presentation: A 42 year-old woman presented with intermittent dry cough of 10 months duration. Her breathing sound was slightly coarse without rales or rhonchi on auscultation. CT scan revealed a right anterior mediastinal shadow with multiple pulmonary nodular lesions. A video-assisted thoracoscopic surgery (VATS) was performed. Histopathology showed it to be a myeloma. Conclusion: This is the first presentation of EMP with a mediastinal mass with multiple pulmonary nodules.
Background Extramedullary plasmacytoma (EMP) is a plasma cell neoplasm of soft tissue without bone marrow involvement or other systemic characteristics of multiple myeloma [1-3]. It is rare and mainly involves the upper aero-digestive tract. Herein we report an extremely unusual presentation as a mediastinal mass and multiple pulmonary nodules, but without bone marrow involvement or other characteristics of multiple myeloma.
bone pain, anorexia, dyspnea on exertion or body weight loss was noted. She took some medicines at a local clinic to control her cough. However, blood-tinged sputum appeared one month prior to hospital admission. No bone pain or lymphadenopathy was noted on examination. Her breathing was slightly coarse without rales or rhonchi on auscultation. A chest X-ray (Figure 1) and computed tomography (CT) (Figure 2A, B) revealed a right anterior mediastinal shadow with multiple pulmonary nodular lesions.
Case presentation A 42 year-old woman presented with intermittent dry cough of ten months duration. No fever, chest tightness,
Tracing back her history, she was a non-smoker, withou
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