Factors influencing the fascial closure rate after open abdomen treatment: Results from the European Hernia Society (Eur
- PDF / 1,105,299 Bytes
- 13 Pages / 595.276 x 790.866 pts Page_size
- 111 Downloads / 192 Views
ORIGINAL ARTICLE
Factors influencing the fascial closure rate after open abdomen treatment: Results from the European Hernia Society (EuraHS) Registry Surgical technique matters A. G. Willms1 · R. Schwab1 · M. W. von Websky2 · F. Berrevoet3 · D. Tartaglia4 · K. Sörelius6,7 · R. H. Fortelny8,9 · M. Björck5 · T. Monchal10 · F. Brennfleck11 · D. Bulian12 · C. Beltzer13 · C. T. Germer14 · J. F. Lock14 · EURAHS Open Abdomen Group Received: 21 August 2020 / Accepted: 2 November 2020 © The Author(s) 2020
Abstract Purpose Definitive fascial closure is an essential treatment objective after open abdomen treatment and mitigates morbidity and mortality. There is a paucity of evidence on factors that promote or prevent definitive fascial closure. Methods A multi-center multivariable analysis of data from the Open Abdomen Route of the European Hernia Society included all cases between 1 May 2015 and 31 December 2019. Different treatment elements, i.e. the use of a visceral protective layer, negative-pressure wound therapy and dynamic closure techniques, as well as patient characteristics were included in the multivariable analysis. The study was registered in the International Clinical Trials Registry Platform via the German Registry for Clinical Trials (DRK00021719). Results Data were included from 630 patients from eleven surgical departments in six European countries. Indications for OAT were peritonitis (46%), abdominal compartment syndrome (20.5%), burst abdomen (11.3%), abdominal trauma (9%), and other conditions (13.2%). The overall definitive fascial closure rate was 57.5% in the intention-to-treat analysis and 71% in the per-protocol analysis. The multivariable analysis showed a positive correlation of negative-pressure wound therapy (odds ratio: 2.496, p
Data Loading...
