Feasibility, safety and long-term outcomes of complex left main bifurcation treatment using the nano-inverted-t stenting
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ORIGINAL PAPER
Feasibility, safety and long‑term outcomes of complex left main bifurcation treatment using the nano‑inverted‑t stenting: a multicentre prospective registry Gianluca Rigatelli1 · Marco Zuin1,2 · Dobrin Vassilev3 · Huy Dinh4 · Fabio Dell’Avvocata1 · Nguyen Van Tan5 · Nguyen Nghia6 · Federico Ronco7 · Loris Roncon8 Received: 4 May 2020 / Accepted: 10 November 2020 © Springer Nature B.V. 2020
Abstract The role of double stenting techniques in distal bifurcation left main (LM) disease has gaining interest over the latest years. We present the 3-year multicentre registry outcomes of dual stenting using ultra-thin strut stents and the NanoInverted-T (NIT) technique in complex unprotected true LM bifurcation disease. We analysed the procedural and medical data of consecutive patients enrolled between 1st January 2014 and 1st December 2019 in a multicentre registry for complex LM bifurcation disease treated with the double stenting technique called NIT due contraindications and/ or refusal to surgical treatment. Target lesion failure (TLF) was defined as the composite of cardiovascular death, target-vessel MI (TVMI) and clinically driven target lesion revascularization (TLR). Among two hundred-ninety-five patients (138 males, mean age 70.3 ± 12.8 years), post-operative success was achieved in 100% of cases. Contrast volume, procedural time, and radiation exposure were 139.2 ± 23.4 ml, 15.3 ± 4.9 min, and 1080 ± 1034 cGy/m2, respectively. At a mean follow-up of 39.5 ± 0.6 months TLF rate was 6.1% (n = 18) while TLR and cardiovascular mortality rates were 3.0 (n = 9) and 2.6% (n = 8), respectively. Clinically-driven angiographic follow-up was available in 26.4% of patients at a mean time from the procedure of 7.5 ± 0.4 months. Clinically restenosis rate was 3.3%. Revascularization of complex LM bifurcation disease using the NIT double stenting technique resulted feasible and safe with a low incidence of TLF, excellent survival rate and no stent thrombosis. Keywords Left main · Bifurcation stenting · DES · Complex bifurcation
1
Cardiovascular Diagnosis and Endoluminal Interventions, Rovigo General Hospital, Viale Tre Martiri 140, 45100 Rovigo, Italy
2
School of Medicine, University of Ferrara, Ferrara, Italy
Dobrin Vassilev [email protected]
3
Head of Cardiology, Alexandroska University Hospital Medical School, Sofia, Bulgaria
Huy Dinh [email protected]
4
Department of Interventional Cardiology, Tam Duc Heart Hospital, Ho Chi Minh City, Vietnam
Nguyen Van Tan [email protected]
5
Department of Interventional Cardiology, Thong Nhat Hospital, Ho Chi Minh City, Vietnam
6
Department of Interventional Cardiology, Cho Ray Hospital, Ho Chi Minh City, Vietnam
Federico Ronco [email protected]
7
Interventional Cardiology Unit, Department of Cardiology, Mestre Hospital, Mestre, Italy
Loris Roncon [email protected]
8
Division of Cardiology, Rovigo General Hospital, Rovigo, Italy
* Gianluca Rigatelli [email protected]; [email protected] Ma
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