Giant Cell Arteritis

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Sana Loue Martha Sajatovic (Eds.)

Encyclopedia of Aging and Public Health Core Editors: Siran Koroukian, Linda S. Lloyd, Scott Ober, Laura Weiss Roberts, Lori B. Siegel

With 10 Figures and 19 Tables

Sana Loue, JD, PhD, MPH Case Western Reserve University School of Medicine Cleveland, Ohio Martha Sajatovic, MD University Hospitals Case Medical Center Case Western Reserve University School of Medicine Cleveland, Ohio

ISBN-13: 978-0-387-33753-1 This publication is available also as: Electronic publication under 978-0-387-33754-8 and Print and electronic bundle under ISBN 978-0-387-35419-4 Library of Congress Control Number: 2007931335 All rights are reserved. This work may not be translated or copied in whole or in part without the written permission of the publisher (Springer Science+Business Media, LLC, 233 Spring Street, New York, NY 10013, USA), except for brief excerpts in connection with reviews or scholarly analysis. Use in connection with any form of information storage and retrieval, electronic adaption, computer software, or similar or dissimilar methodology now known or hereafter developed is forbidden. The use in this publication of trade names, trademarks, service marks, and similar terms, even if they are not identified as such, is not to be taken as an expression of opinion as to whether or not they are subject to proprietary rights. Springer is part of Springer Science+Business Media springer.com #

2008 Springer Science+Business Media, LLC.

Product liability: The publishers cannot guarantee the accuracy of any information about the application of operative techniques and medications contained in this book. In every individual case the user must check such information by consulting the relevant literature. Editor: Bill Tucker, New York; Thomas Mager, Heidelberg Development Editor: Susanne Friedrichsen, Heidelberg Production Editor: Christian Kopecki, Frank Krabbes, Heidelberg Cover Design: Joseph Piliero, NYC; Erich Kirchner, Heidelberg; Frido Steinen-Broo, Barcelona, de’blik, Berlin

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Editors-in-Chief Sana Loue, JD, PhD, MPH Case Western Reserve University School of Medicine Cleveland, Ohio

Martha Sajatovic, MD University Hospitals Case Medical Center Case Western Reserve University School of Medicine Cleveland, Ohio

Core Editors Siran Koroukian, PhD Case Western Reserve University School of Medicine Cleveland, Ohio Linda S. Lloyd, Dr. P.H. Alliance Healthcare Foundation San Diego, California Scott Ober, MD, MBA Veterans Affairs Medical Center Cleveland, Ohio

Laura Weiss Roberts, MD Medical College of Wisconsin Milwaukee, Wisconsin Lori B. Siegel, MD, FACP, FACR Rosalind Franklin University of Medicine North Shore Rheumatology Lake Forest, Illinois

Table of Contents

I. Foundation Topics Biology of Aging . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 Teresa Dolinar The History and De

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