Histiocytic Fibroma
It is an innocuous lesion originating eccentrically in the growing metaphysis and composed of histio-fibroblasts. It is usually asymptomatic and spontaneously regressing.
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SOFT TISSUE TUMORS
Front cover: Logo of the lstituto Ortopedico Rizzoli, S. Michele in Bosco, Bologna
MARIO CAMPANACCI (13-01-1932 - 16-01-1999)
MARIO CAMPANACCI Director of the 1st Orthopaedic Clinic, Rizzoli Orthopaedic Institute, Bologna
BONE AND
SOFT TISSUE TUMORS Clinical Features, Imaging, Pathology and Treatment Foreword by William F. Enneking Second, completely revised edition
Springer-Verlag Wien GmbH
Mario Campanacci, M.D. Orthopaedic Surgeon, Professor of Orthopaedic Surgery and Pathology, University of Bologna; Director of the l st Orthopaedic Clinic, Rizzoli Orthopaedic Institute, Bologna; Director of the Graduate School of Orthopaedics, University of Bologna; Director of the Tumor Centre, Rizzoli Orthopaedic Institute, Bologna
William F. Enneking, M.D. Eugene Jewett Professor of Orthopaedic Surgery and Pathology; Distinguished Service Professor, College of Medicine, University of Florida
BONE AND SOFf TISSUE TUMORS Second, completely revised edition This work is a co-publication by Pieein Nuova Libraria- Padova and by Springer-Verlag Wien GmbH and is subject to copyright. All rights are reserved, whether the whole or part of the material is concemed, specifically those of translation, reprinting, re-use of illustrations, broadcasting, reproduction by photocopying machine or similar means, and storage in data banks. © 1999 Springer-Verlag Wien Ursprünglich erschienen bei Springer-Verlag Wien New York 1999 Softcover reprint of the hardcover 2nd edition 1999
Exclusive distribution rights outside ltaly: Springer-Verlag Wien GmbH
With 1120 Figures ISBN 978-3-7091-3848-9 ISBN 978-3-7091-3846-5 (eBook) DOI 10.1007/978-3-7091-3846-5
SPIN 10685488 ISBN 978-3-7091-3848-9
COD. 0301520
CONTENTS
Foreword to the first edition by W.F. Enneking· · · · · · · · · · · · · · · · · · · · · · · · · · · · XV Preface to the first edition (1990) · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · XV/1 Preface to the second edition ( 1999) · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · XIX
1. Introduction
1
Terminology .
1 1 1
Hyperplasia (reactive or reparative process). Hamartoma, dysplasia . . . . Benign tumor . . . . . . . . . Low-grade malignant tumor . High-grade malignant tumor . Metaplasia . . . . . . . . . . Anaplasia . . . . . . . . . . . Tumor progression, dedifferentiation Periosteal, parosteal, juxtacortical . .
Normal ultrastructure of the cell . . . Normal tissues and their embryonal development . Fibroblasts, myofibroblasts, fibrocytes Histiocytes and macrophages . . . Chondroblasts, chondrocytes. . . . Osteoblasts, osteocytes, osteoclasts Smooth muscle cells . . . . . . Striated (skeletal) muscle cells . . . Lipoblasts, lipocytes . . . . . . . . Angioblasts, vascular endothelium, pericytes, glomus bodies . Synovium . . . . . . . . . Mast cells . . . . . . . . . Neural crest derived cells .
Tumor classification Frequency . . . . . . Bone tumors. . . . Soft tissue tumors .
Data (other than biopsy) contributory to diagnosis. History and clinical featur
