Hospital mortality in mechanically ventilated COVID-19 patients in Mexico

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Hospital mortality in mechanically ventilated COVID‑19 patients in Mexico Silvio A. Ñamendys‑Silva1,2*  , Alan Gutiérrez‑Villaseñor3 and Juan P. Romero‑González3 © 2020 Springer-Verlag GmbH Germany, part of Springer Nature

Dear Editor, As of August ­13th, 2020, a total of 20,439,814 confirmed cases of coronavirus disease 2019 (COVID-19) have been reported to the World Health Organization, and 744,385 lives have been lost [1]. The Americas constitute the current epicentre of the COVID-19 pandemic. A total of 505,751 confirmed cases of COVID-19 and 55,293 deaths have been reported in Mexico [2], and 2.5% of these patients have required endotracheal intubation and invasive mechanical ventilation [2]. This report describes the sociodemographic characteristics and comorbidities associated with mortality in mechanically ventilated adults with COVID-19 in Mexico. We analysed data collected in the General Epidemiology Directorate of the Mexican Ministry of Heath, which is an open-source dataset comprising of daily updated data of suspected COVID-19 cases that were confirmed by a positive test for SARS-CoV-2 [2]. We used the version released on August ­13th, 2020 [2]. A total of 12,018 mechanically ventilated adults with COVID-19 were included. The flow chart of the study is shown in Figure S1 (supplemental methods). The median age was 60  years (interquartile range 50–69; range 18–108  years), and 7971 (66.3%) were men (Figure S2) (supplementary material). The sociodemographic characteristics and comorbidities of the patients with COVID-19 (according to in-hospital deaths) are shown in Table 1. A total of 57.6% (n = 6928) of the patients were mechanically ventilated outside of the intensive care

*Correspondence: [email protected] 1 Division of Pulmonary, Anesthesia and Critical Care Medicine, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, 14000 Mexico City, Mexico Full author information is available at the end of the article

units (Figure S1)  (supplementary material). The overall in-hospital mortality was 73.7% (n = 8861). In our report, hospital mortality was higher than mortality in high-income countries such as the United Kingdom (67.4% versus 73.7%, p