Impact of COVID-19 on health-related quality of life in patients with cardiovascular disease: a multi-ethnic Asian study
- PDF / 942,071 Bytes
- 7 Pages / 595.276 x 790.866 pts Page_size
- 14 Downloads / 176 Views
Open Access
RESEARCH
Impact of COVID‑19 on health‑related quality of life in patients with cardiovascular disease: a multi‑ethnic Asian study Shir Lynn Lim1,2* , Kai Lee Woo1, Eleanor Lim1, Faclin Ng1, Mark Y. Chan1,2 and Mihir Gandhi3,4,5
Abstract Background: Little is known about the impact of the global coronavirus disease-2019 (COVID-19) pandemic on patients with cardiovascular disease (CVD), the biggest global killer and major risk factor for severe COVID-19 infections. We aim to explore the indirect consequences of COVID-19 on health-related quality of life (HRQoL) of patients with CVD. Methods: Eighty-one adult outpatients with CVD were assessed using the EQ-5D, a generic health status instrument with five dimensions (mobility, self-care, usual activities, pain/discomfort, anxiety/depression), before and during the pandemic. Changes in the EQ-5D dimensional responses were compared categorically as well as using the dimension-specific sum-score (range 1–3, with a higher score indicating worse health). The responses and sum-score were compared using the exact test of symmetry and the paired t-test, respectively. Results: These patients [mean age (SD) 59.8 (10.5); 92.6% males; 56% New York Heart Association (NYHA) functional class I] had coronary artery disease (69%), heart failure (28%), or arrhythmias (15%). None experienced change in NYHA class between assessments. About 30% and 38% of patients reported problems with at least one of the EQ-5D dimensions pre-pandemic and during the pandemic, respectively. The highest increase in health problems was reported for anxiety/depression (12.5% pre-pandemic vs 23.5% during pandemic; p = 0.035) with mean domain-specific score from 1.12 (SD 0.33) to 1.25 (SD 0.46) (standardized effect size = 0.373, p = 0.012). There was no meaningful change in other dimensions as well as overall HRQoL. Conclusion: The COVID-19 pandemic is associated with a significant worsening of the mental health of patients with CVD. Keywords: COVID-19, Health-related quality of life, Cardiovascular, EQ-5D, Psychological health Introduction Coronavirus disease 2019 (COVID-19) is a global pandemic with unprecedented medical, economic and social consequences. Much attention has been on the potentially severe cardiovascular complications associated with COVID-19 [1, 2]; patients with pre-existing *Correspondence: [email protected] 1 Department of Cardiology, National University Heart Center, Singapore, Singapore Full list of author information is available at the end of the article
cardiovascular disease (CVD) also suffer worse outcomes with COVID-19 infection [3]. Beyond these direct consequences, COVID-19 has reshaped the delivery of cardiovascular care—non-critical and elective procedures are postponed, and distancing imperatives have led to rapid scaling of telemedicine and cancellation of cardiac rehabilitation. The repeated public health messages that those with chronic conditions should practice social and physical distancing may adversely affect the health-seeking behavior of p
Data Loading...
