Incidence and locations of deep venous thrombosis of the lower extremity following surgeries of tibial plateau fractures
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(2020) 15:605
RESEARCH ARTICLE
Open Access
Incidence and locations of deep venous thrombosis of the lower extremity following surgeries of tibial plateau fractures: a prospective cohort study Junyong Li1,2,3,4,5†, Yanbin Zhu1,2,3,5†, Wei Chen1,2,3,5†, Kuo Zhao1,2,3,5, Junzhe Zhang1,2,3,5, Hongyu Meng1,2,3,5, Zhucheng Jin1,2,3,5, Dandan Ye2,3,5 and Yingze Zhang 1,2,3,5*
Abstract Objective: To investigate the incidence of deep venous thrombosis (DVT) of the lower extremities following surgeries of tibial plateau fractures. Methods: Retrospective analysis of the prospectively collected data on patients undergoing surgeries of tibial plateau fractures between October 2014 and December 2018 was conducted. Duplex ultrasonography (DUS) was used to screen for postoperative DVT of the bilateral lower extremities. Data on demographics, comorbidities, injury, surgery, and laboratory biomarkers at admission were collected. Univariate analyses and multivariate logistic regression analyses were used to identify the independent risk factors associated with DVT. Results: Among 987 patients included, 46 (4.7%) had postoperative DVT, with incidence rate of 1.0% for proximal and 3.7% for distal DVT. The average interval between operation and DVT was 8.3 days (median, 5.8 days), ranging from 2 to 42 days. DVT involved the injured extremity in 39 (84.8%) patients, both the injured and uninjured extremity in 2 patients (4.3%) and only the uninjured extremity in 5 patients (10.9%). Five risk factors were identified to be associated with postoperative DVT, including age (≥ 41 vs < 41 years) (OR 3.08; 95% CI 1.43–6.61; p = 0.004), anesthesia (general vs regional) (OR 2.08; 95% CI 1.12–3.85; p = 0.021), hyponatremia (OR 2.21; 95% CI 1.21–4.06; p = 0.010), prolonged surgical time (OR 1.04; 95% CI 1.01–1.07; p = 0.017) and elevated D-dimer level (OR 2.79; 95% CI 1.34–4.83; p = 0.004). Conclusion: These epidemiologic data may be helpful in individualized assessment, risk stratification, and development of targeted prevention programs. Keywords: Deep venous thrombosis, Surgical intervention, Tibial plateau fractures, Incidence, Risk factors
* Correspondence: [email protected] † Junyong Li, Yanbin Zhu and Wei Chen contributed equally to this work. 1 Department of Orthopaedic Surgery, The 3rd Hospital of Hebei Medical University, Shijiazhuang 050051, Hebei, PR China 2 Key Laboratory of Biomechanics of Hebei Province, Shijiazhuang 050051, Hebei, PR China Full list of author information is available at the end of the article © The Author(s). 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a cred
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