Increased 18 F-fluorodeoxyglucose accumulation in bilateral adrenal glands of the patients suffering from vasovagal reac
- PDF / 1,694,329 Bytes
- 5 Pages / 595.276 x 790.866 pts Page_size
- 67 Downloads / 168 Views
ORIGINAL ARTICLE
Increased 18F-fluorodeoxyglucose accumulation in bilateral adrenal glands of the patients suffering from vasovagal reaction due to blood vessel puncture Yoichi Otomi1 • Takayoshi Shinya1 • Hideki Otsuka2 • Kaori Terazawa1 Saho Irahara1 • Saki Nagase1 • Ayaka Takahashi1 • Michiko Kubo1 • Masafumi Harada1
•
Received: 29 February 2016 / Accepted: 21 May 2016 / Published online: 2 June 2016 Ó The Japanese Society of Nuclear Medicine 2016
Abstract Objective The purpose of the study was to evaluate the hypothesis that patients having a vasovagal reaction (VVR) after blood vessel puncture show increased FDG accumulation in bilateral adrenal glands. Methods Over the past 8 years, 26 patients experienced a VVR after blood vessel puncture following intra-venous injection of FDG at our institution. Of the 26 patients, 16 underwent multiple-occasion FDG-PET/CT scans while suffering a VVR at only one examination. All 16 patients had no morphological abnormality in the adrenal glands on FDG-PET/CT and follow-up examination. For the 16, we retrospectively reviewed the FDG-PET/CT scan with respect to the adrenal glands and compared the result to that for the FDG-PET/CT scan of the same patient when there was no VVR event. We used both visual analysis and semi-quantitative analysis employing either maximum standardized uptake value (SUVmax) or adrenal-to-liver (A/L) SUVmax ratio. Results On visual analysis of the FDG-PET/CT with VVR, accumulations in both of the adrenal glands was judged positive, defined as higher than the hepatic accumulation, in 84 % of the cases. The SUVmax in the right adrenal gland was 2.79 ± 0.69 with VVR and 1.92 ± 0.33 without VVR; this value in the left adrenal gland was 3.07 ± 0.71
& Yoichi Otomi [email protected] 1
Department of Radiology, Tokushima University Hospital, Tokushima, 2-50-1 Kuramoto-cho, Tokushima 770-8503, Japan
2
Department of Medical Imaging/Nuclear Medicine, Institute of Biomedical Sciences, Tokushima University Graduate School, Tokushima, Japan
with VVR and 2.05 ± 0.39 without. Mean SUVmax of both adrenal glands was 2.93 ± 0.66 with VVR and 1.98 ± 0.35 without. The A/L SUVmax ratio in the right adrenal gland was 1.02 ± 0.26 with VVR and 0.69 ± 0.11 without; this value in the left was 1.11 ± 0.23 with VVR and 0.74 ± 0.15 without. The mean A/L SUVmax ratio of both adrenal glands was 1.06 ± 0.24 with VVR and 0.72 ± 0.13 without. Each parameter with VVR was significantly higher than that without. For the two adrenal glands, the mean SUVmax with VVR was 48 % higher than that without VVR. Conclusions We confirmed the hypothesis that patients having a VVR after blood vessel puncture show increased FDG accumulation in their bilateral adrenal glands. This may reflect hyper-metabolism of the adrenal glands in synthesizing and secreting catecholamine. Keywords FDG PET/CT Adrenal gland Vasovagal reaction Vagal reflex
Introduction Eighteen-fluorine fluorodeoxyglucose (F-18 FDG) positron emission tomography/computed tomography (PET/CT) has been widely u
Data Loading...
