Iodine-131

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Blockage of nasolacrimal gland: case report A 58-year-old man had blockage of nasolacrimal gland following treatment with iodine-131 for papillary thyroid cancer. The man who had Non-Hodgkin’s lymphoma was found a mildly avid focus on surveillance 18FDG PET/CT after successful therapy for lymphoma. With a diagnosis of papillary thyroid cancer, classical type, he underwent total thyroidectomy. As per his consent, he underwent radioactive iodide treatment (RAIT). He received 100 mCi of iodine-131 for remnant ablation (RA). The posttreatment scan showed two cervical foci of uptake in the identical position to D-RAIS, one was higher in the right neck and the other one located more inferior and close to the midline. However, a small focus was noted in the head to the right of midline, which was in a typical pattern of activity accumulated in the blocked nasolacrimal gland. The blockage of nasolacrimal gland was considered as a side effect of iodine-131 therapy. Thereafter, the man was referred to ophthalmology. For blockage, he underwent successful dacryocystorhinostomy. At one year follow-up, he showed successful ablation [time to reaction onset not stated]. Slonimsky E, et al. Radiotheragnostics paradigm for radioactive iodine (Iodide) management of differentiated thyroid cancer. Current Pharmaceutical Design 26: 3812-3827, 803501161 No. 31, 5 Jun 2020. Available from: URL: http://doi.org/10.2174/1381612826666200605121054

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Reactions 12 Sep 2020 No. 1821

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