Julien Ivor Ellis Hoffman
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IN MEMORIAM
Julien Ivor Ellis Hoffman
© Springer Science+Business Media, LLC, part of Springer Nature 2020
Sadly, Julien Hoffman died on June 23, 2020. He was born in Salisbury (now Harare), Southern Rhodesia (now Zimbabwe) in 1925. He received the degree of B.Sc. (Hon) in 1945 and graduated cum laude from the Medical School of the University of the Witwatersrand in Johannesburg, South Africa, in 1949 and began an internship in Internal Medicine at the Johannesburg General Hospital. In 1952, he was an intern and then a Registrar in Internal Medicine at Central Middlesex Hospital in London. He returned to Johannesburg in 1955 to a position of Registrar in Internal Medicine at the General Hospital. His career in Cardiology was initiated as a Research Fellow at the Royal Postgraduate Medical School in London in 1957. He then moved to the USA in 1959 as a Fellow in Pediatric Cardiology at the Children’s Hospital, Boston, and in 1960 was a Fellow in the Cardiovascular Research Institute at the University of California, San Francisco. He returned to Rhodesia to practice clinical cardiology, but returned to the USA in 1962 to join Abraham Rudolph in the Pediatric Cardiology Division of the Department of Pediatrics at Albert Einstein College of Medicine in New York. In 1966, Rudolph and Hoffman joined the Pediatric Department at the University of California in San Francisco (UCSF) and also were appointed as Senior Staff of the Cardiovascular Research Institute. Although their clinical interests in Pediatric Cardiology were similar, Rudolph’s research interests centered on fetal and neonatal
cardiovascular function, whereas Hoffman was primarily interested in physiology of the coronary circulation; separate research laboratories were established. After 32 years, he became an Emeritus Professor in 1994, but continued to actively participate in clinical care and, particularly, teaching. He also continued to consult with and advise former Fellows and to contribute to the literature. During achievement of the B.Sc. degree, Hoffman developed his first interests in research, directed to studies of spermatogenesis. He also began to appreciate the importance of statistics. While in Johannesburg, he assisted members of the faculty in Medicine in statistical analysis and expanded his expertise by association with John Kerrich, chief of the Statistics Department at the University of the Witwatersrand. In 1964, he introduced a course in statistics for Fellows in the Cardiovascular Research Institute and taught this course for about 30 years. He was a member of the Biostatistics Group of UCSF, responsible for coordinating statistics practice and also served as a consultant in statistics for several medical journals. In 2015, he published the book “Biostatistics for Medical and Biomedical Practitioners,” which reviews the basic aspects, the applications, and the reliability of statistics. Early in his career in Pediatric Cardiology, Hoffman reported on the high incidence of spontaneous closure of ventricular septal defects, particularl
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