Knee intra-articular extraskeletal aneurysmal bone cyst: a case report and review of literature

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Knee intra-articular extraskeletal aneurysmal bone cyst: a case report and review of literature Noam Olshinka 1,2 & Yusef Azraq 3 & Stephanie Benshushan 4 & Omer Or 2 Received: 1 March 2020 / Revised: 4 May 2020 / Accepted: 5 May 2020 # ISS 2020

Abstract Aneurysmal bone cyst (ABC) is a benign locally destructive lesion that usually developed in the bone cavity of bones, less commonly on the surface of cortical bones and very rarely develop outside the bone. There are only 35 reports of extraskeletal aneurysmal bone cyst (ESABC) in the English literature. We report a case of a 12-year-old female with no history of trauma who presented with knee pain. Imaging studies revealed an infrapatellar mass that was fast to calcify during a period of 3 months. MRI showed high T2 center, low T1 signal, and heterogenic enhancement with a rim of low intensity consistent with calcified boarders surrounded by severe soft tissue edema. The lesion was surgically excised, and a histological examination revealed an aneurysmal bone cyst possibly arising within myositis ossificans or heterotopic ossification. In her last follow-up 1.5 years after the surgical excision, the patient was symptom free and without signs of recurrence. To the best of our knowledge, this is the first reported case of an intra-articular ESABC located in the knee. Keywords Aneurysmal bone cyst . Extraskeletal aneurysmal bone cyst . Myositis ossificans . Knee . Soft tissue . Radiograph . MRI

Introduction Aneurysmal bone cyst (ABC) is a benign lesion which is found most commonly in bones. It composed of blood-filled spaces separated by connective tissue septa containing fibroblasts, osteoclast-type giant cells, and reactive woven bone. It can appear at any age but usually arise in the first two decades of life. It has no sex predominance. It is usually locally destructive and cause pain and swelling in the metaphysis of long bones, most commonly in the femur, tibia, humerus, and the posterior elements of vertebral bodies [1].

ABCs most commonly develop in the medullary cavity of bones. Less common presentation is on the surface of cortical bones [2, 3]. In extremely rare cases, ABC may present in soft tissue. These rare cases of extraskeletal aneurysmal bone cyst (ESABC) can be confused with other soft tissue tumors such as myositis ossificans, tenosynovial giant cell tumor, brown tumor, and extraskeletal telangiectatic osteosarcoma [4]. To our knowledge, intra-articular ESABC has not been reported. We present the first reported case of an intra-articular ESABC and a review of the literature.

Case report * Noam Olshinka [email protected] 1

Department of Orthopedic surgery, Hôpital Maisonneuve-Rosemont, Université de Montréal, Montréal, Québec, Canada

2

Department of Orthopedic surgery, Hadassah-Hebrew University Medical Center, Jerusalem, Israel

3

Department of Radiology, Hadassah-Hebrew University Medical Center, Jerusalem, Israel

4

Department of Pathology, Hadassah-Hebrew University Medical Center, Jerusalem, Israel

A 12-year-old gir