Landmark Trials in Oncology
This book describes the evolution of treatment in oncology through the lens of approximately 250 landmark clinical trials. The well-designed clinical trial is essential to the practice of medicine. There is no field that has embraced or been transformed m
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Landmark Trials in Oncology
Santosh Yajnik
Landmark Trials in Oncology
Santosh Yajnik Radiation Oncology Consultants (ROC) Chicago, IL USA
ISBN 978-3-030-14404-3 ISBN 978-3-030-14405-0 (eBook) https://doi.org/10.1007/978-3-030-14405-0 Library of Congress Control Number: 2019936578 © Springer Nature Switzerland AG 2019 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors, and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. This Springer imprint is published by the registered company Springer Nature Switzerland AG The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland
Preface
The well-designed clinical trial is essential to the field of medicine. While doing my residency training in radiation oncology several years ago at Memorial Sloan Kettering Cancer Center, there was a daily morning conference during which trainees were expected to have the important details of landmark clinical trials committed to memory. Having practiced radiation oncology for the past 15 years, I have seen the tremendous impact that well- designed clinical trials have made on the field of oncology. Both the initial respect for well-designed clinical trials engendered through rigorous training and the first-hand experience of seeing how clinical trials improve the lives of my patients have created in me a deep respect for the well-designed clinical study. This book summarizes key findings from approximately 250 landmark clinical trials in oncology. The author makes no claims toward completeness. This selection of trials reflects the knowledge base, clinical and intellectual interests and training of the author who is a radiation oncologist. However, precisely because oncology is a multidisciplinary endeavor, these studies should be of interest to radiation oncologists, surgeons, medical oncologists, and other physicians interested in learning more about the trials that have impacted oncology. The reader i
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