Laparoscopic cholecystectomy for acute cholecystitis: is the surgery still safe beyond the 7-day barrier? A multicentric

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ORIGINAL ARTICLE

Laparoscopic cholecystectomy for acute cholecystitis: is the surgery still safe beyond the 7‑day barrier? A multicentric observational study Marcello Di Martino1 · Ismael Mora‑Guzmán1,12 · Víctor Vaello Jodra2 · Alfonso Sanjuanbenito Dehesa2 · Dieter Morales‑García3 · Rubén Caiña Ruiz3 · Francisca García‑Moreno Nisa4 · Fernando Mendoza‑Moreno4 · Sara Alonso Batanero5 · José Edecio Quiñones Sampedro5 · Paola Lora Cumplido6 · Altea Arango Bravo6 · Ines Rubio‑Perez7 · Luis Asensio‑Gomez7 · Fernando Pardo Aranda8 · Sara Sentí i Farrarons8 · Cristina Ruiz Moreno9 · Clara Maria Martinez Moreno9 · Aingeru Sarriugarte Lasarte10 · Mikel Prieto Calvo10 · Daniel Aparicio‑Sánchez11 · Eduardo Perea del Pozo11 · Elena Martin‑Perez1

© Italian Society of Surgery (SIC) 2020

Abstract Timing for early laparoscopic cholecystectomy (ELC) in patients with acute calculous cholecystitis (ACC) is still controversial. This study assesses ELC for ACC with delayed presentation, according to hospital volume. Multicentric retrospective analysis of 1868 ELC. Patients were classified into two groups according to the timing of surgery from clinical onset and centre volume. Group 1 (G1) within the first 7 days, group 2 (G2) beyond that. Then centres were classified in low volume centres (LVC) and higher volume centres (HVC) according to the number of ELC performed per year. Overall, G2 showed increased conversion rate (17.7% vs 10.7%; p = 0.004), intraoperative complications (7.3% vs 2.9%; p = 0.001); postoperative haemorrhage (3.6% vs 0.8%; p