Ledipasvir/sofosbuvir/ribavirin

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Upper gastrointestinal bleeding: case report In a prospective study conducted between May 2017 and February 2018, in which 88 patients with decompensated liver cirrhosis with virus C (LC VC) were admitted to a hospital in Romania, one patient [age and sex not stated] was described, who developed upper gastrointestinal bleeding during treatment with ledipasvir/sofosbuvir and ribavirin. The patient, who had LC VC, started receiving treatment with oral ledipasvir/sofosbuvir and ribavirin [dosages not stated]. However, the patient developed upper gastrointestinal bleeding [duration of treatment to reaction onset not stated], requiring emergency hospitalisation. Therefore, therapy with ledipasvir/sofosbuvir and ribavirin was discontinued [outcome not stated]. Cuciureanu T, et al. Cessation of oral antiviral treatment in patients with decompensated liver cirrhosis with virus C. Journal of Gastrointestinal and Liver Diseases 27 (Suppl. 803497671 2): 50-51, May 2018. Available from: URL: https://www.jgld.ro/jgld/index.php/jgld [abstract]

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Reactions 22 Aug 2020 No. 1818

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