Living with Chronic Disease: Measuring Important Patient-Reported Outcomes
This book serves as a roadmap for the development and application of patient-reported outcome (PRO) measures, supporting beginners through to experts, as a practical guide. To elucidate on key concepts in the book, examples from clinical research in hyper
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Living with Chronic Disease: Measuring Important Patient-Reported Outcomes Foreword by: Theresa Mullin, FDA
Living with Chronic Disease: Measuring Important Patient-Reported Outcomes
Paul Kamudoni Nutjaree Johns Sam Salek
Living with Chronic Disease: Measuring Important Patient-Reported Outcomes
Paul Kamudoni Global Evidence & Value Development – R&D, Merck KgaA Darmstadt Germany
Nutjaree Johns Faculty of Pharmaceutical Sciences Khon Kaen University Khon Kaen Thailand
Sam Salek School of Life & Medical Sciences University of Hertfordshire Hatfield Hertfordshire United Kingdom
Institute of Medicines Development Cardiff United Kingdom
ISBN 978-981-10-8413-3 ISBN 978-981-10-8414-0 (eBook) https://doi.org/10.1007/978-981-10-8414-0 Library of Congress Control Number: 2018940259 © Springer Nature Singapore Pte Ltd. 2018 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. Printed on acid-free paper This Adis imprint is published by the registered company Springer Nature Singapore Pte Ltd. The registered company address is: 152 Beach Road, #21-01/04 Gateway East, Singapore 189721, Singapore
Foreword
We live in an era of exciting discovery and innovation in biomedical science and technology. The resulting medical breakthroughs are providing safe and effective treatments for often serious and life-threatening diseases and are thus transforming lives. Notwithstanding and often because of this progress, the number of patients living with chronic disease continues to grow. A recent analysis by the Global Burden of Disease Study (GBD) found that although death rates for most causes have declined worldwide since 1990, there has not been a similar decline in age-standardized years lived with disability (YLD) rates. For many causes, YLD rates have either remained the same or have increased, and the increasing prevalence of disabling disease produces increased dema
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