Lobular neoplasia occult on conventional imaging and diagnosed on MRI-guided biopsy: can we estimate upgrade on surgical
- PDF / 849,455 Bytes
- 10 Pages / 595.276 x 790.866 pts Page_size
- 10 Downloads / 150 Views
EPIDEMIOLOGY
Lobular neoplasia occult on conventional imaging and diagnosed on MRI‑guided biopsy: can we estimate upgrade on surgical pathology? Yoav Amitai1 · Tehillah S. Menes2 · Anabel Scaranelo1 · Rachel Fleming1 · Supriya Kulkarni1 · Sandeep Ghai1 · Tulin Cil3 · Susan Done4 · Vivianne Freitas1 Received: 26 June 2020 / Accepted: 18 August 2020 © Springer Science+Business Media, LLC, part of Springer Nature 2020
Abstract Purpose The goal of this study is to evaluate the frequency and imaging features of lobular neoplasia (LN) diagnosed on MRI-guided biopsy, determine the upgrade rate to malignancy, and assess for any features that may be associated with an upgrade on surgical excision. Materials and methods Research ethical board approved the review of consecutive patients with MRI-detected LN between January 2009 and December 2018 with differentiation between pure LN and LN with associated other high-risk lesions. The final outcome was determined by final pathology results from surgical excision or 24 months of follow-up. Appropriate statistical tests were used. Results Out of 1250 MRI-guided biopsies performed, 76 lesions (6%) fulfilled the inclusion criteria and formed the study cohort. Of the 76 lesions, 54 (71%) were pure LN while the rest had coexistent high-risk lesion. Non-mass enhancement (NME) was the most common lesion type (62, 82%). Fifty-nine lesions (78%) were surgically excised, the other 17 had benign follow-up. Overall, 8 lesions (11%) were upgraded to malignancy on final pathology. Malignant outcome was associated with larger lesion size (5.5 versus 1.9 cm, P
Data Loading...
