Major Neuropsychological Impairments in Schizophrenia Patients: Clinical Implications
- PDF / 342,928 Bytes
- 7 Pages / 595.276 x 790.866 pts Page_size
- 11 Downloads / 196 Views
SCHIZOPHRENIA AND OTHER PSYCHOTIC DISORDERS (AK PANDURANGI, SECTION EDITOR)
Major Neuropsychological Impairments in Schizophrenia Patients: Clinical Implications Mackenzie T. Jones 1
&
Philip D. Harvey 1,2
# Springer Science+Business Media, LLC, part of Springer Nature 2020
Abstract Purpose of Review Schizophrenia is a complex severe mental illness with high morbidity and mortality. It is characterized by positive symptoms, negative symptoms, and cognitive impairment. Cognitive impairment is strongly associated with functional impairment and presents a major barrier to recovery. This article reviews some of the most recent research on cognition in schizophrenia and the clinical implications. Recent Findings There have been recent studies related to the genomics of cognition and neural structures involved in cognition. We review recent investigations into the assessment of social cognition and the implications of impaired introspective accuracy. A recent network analysis assessed the relationship of neurocognition and social cognition to functional capacity. We further discuss the role of specific symptoms in functioning, including negative symptoms and symptoms related to autism spectrum disorder. We conclude with a discussion of a novel computerized treatment for social cognition. Summary Recent research has sought to better understand several dimensions of cognition including genomics, brain structure, social cognition, functional capacity, and symptomatology. This recent research brings us closer to understanding the complex clinical picture of schizophrenia and the best treatments to achieve recovery. Keywords Cognition . Functioning . Genomics . Recovery . Schizophrenia . Social cognition
Introduction Schizophrenia is characterized by positive symptoms, negative symptoms, and cognitive impairment. For decades, treatment focused on the reduction of positive symptoms, but the major aim is now the goal of “recovery.” While symptom reduction is a component of recovery, recovery is a multidimensional concept. Recovery also encompasses social functioning, occupational functioning, and the ability
This article is part of the Topical collection on Schizophrenia and Other Psychotic Disorders * Mackenzie T. Jones [email protected] 1
Department of Psychiatry and Behavioral Sciences, University of Miami Miller School of Medicine, Miami, FL, USA
2
Research Service, Bruce W. Carter VA Medical Center, Miami, FL, USA
to live independently [1]. Thus, recovery requires not only symptom stability but also improvement in functioning. Cognitive impairment has been known for years to be strongly associated with impairments in functioning [2–5]. Within the realm of cognition, there are separate domains that impact real-world functioning. These domains include processing speed, attention/vigilance, working memory, verbal learning and memory, visual learning and memory, reasoning and problem-solving, and social cognition. Of these domains, social cognition is among the strongest known correlates of social functionin
Data Loading...
