Medical and Surgical Complications of Sickle Cell Anemia
This book is a wide-ranging guide to the diagnosis and management of the numerous medical and surgical complications that may arise in patients with sickle cell anemia. After introductory chapters on the genetics, pathophysiology, clinical features, and v
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Ahmed Al-Salem
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Medical and Surgical Complications of Sickle Cell Anemia
Ahmed Al-Salem
Medical and Surgical Complications of Sickle Cell Anemia
Ahmed Al-Salem Department of Surgery Dar A lAlafia Medical Company Qatif Saudi Arabia
ISBN 978-3-319-24760-1 ISBN 978-3-319-24762-5 DOI 10.1007/978-3-319-24762-5
(eBook)
Library of Congress Control Number: 2015957249 Springer Cham Heidelberg New York Dordrecht London © Springer International Publishing Switzerland 2016 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. Printed on acid-free paper Springer International Publishing AG Switzerland is part of Springer Science+Business Media (www.springer.com)
Preface
Sickle cell anemia is one of the common hemoglobinopathies in the world and it results from a single change of amino acid, valine instead of glutamic acid at the 6th position of the 146 amino acids of the beta chain of the hemoglobin. A single change of one amino acid can lead to so much morbidity and mortality. Sickle cell anemia can affect every part of the body leading to so much morbidity and mortality. Awareness of sickle cell anemia and its complications is important for early diagnosis and management, taking into consideration the recent advances in the management of sickle cell anemia including the use of hydroxyurea, bone marrow transplantation, and the promising gene therapy. This book is written as an outline of sickle cell anemia and its medical and surgical complications. It is written in a simple way and easy to read. It covers most aspects of sickle cell anemia with emphasis on the medical and surgical complications of sickle cell anemia and the most important points relevant to the patient’s presentation, diagnosis, and management. This book is well illustrated and includes clinical, operative, radiological, histopathological, and hand-drawn illustrations. I hope this book will be useful to consultant pediatricians, consultant internists, consultant hematologists, specialists, fellows, and resid
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